PPP4R1-AS1

Summary

PPP4R1-AS1 (PPP4R1 antisense RNA 1, HGNC:51112) is a long non-coding RNA gene on chromosome 18p11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51112
Approved symbol	PPP4R1-AS1
Name	PPP4R1 antisense RNA 1
Location	18p11.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263627
Ensembl biotype	lncRNA
Entrez	101927323
RNAcentral	URS000075D56F — lncRNA, 530 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000582435, ENST00000836342, ENST00000836343, ENST00000836344, ENST00000836345, ENST00000836346, ENST00000836347, ENST00000836348, ENST00000836349, ENST00000836350, ENST00000836351, ENST00000836352

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000582435 — 3 exons

Exon	Start	End
ENSE00002690667	9617148	9617285
ENSE00004255692	9614951	9615335
ENSE00004255699	9619195	9619368

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 99.82.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2199 / max 12.5491, expressed in 90 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
169372	0.2199	90

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	99.82	gold quality
left testis	UBERON:0004533	75.57	gold quality
right testis	UBERON:0004534	75.34	gold quality
testis	UBERON:0000473	74.97	gold quality
cortical plate	UBERON:0005343	74.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.67	gold quality
ventricular zone	UBERON:0003053	70.81	gold quality
ganglionic eminence	UBERON:0004023	69.33	gold quality
right lung	UBERON:0002167	67.87	gold quality
lower esophagus mucosa	UBERON:0035834	67.27	gold quality
esophagus mucosa	UBERON:0002469	65.57	gold quality
duodenum	UBERON:0002114	64.91	gold quality
blood	UBERON:0000178	64.73	gold quality
lymph node	UBERON:0000029	63.33	gold quality
esophagus	UBERON:0001043	63.32	gold quality
skeletal muscle tissue	UBERON:0001134	63.02	gold quality
bone marrow	UBERON:0002371	62.43	gold quality
rectum	UBERON:0001052	62.30	gold quality
descending thoracic aorta	UBERON:0002345	61.97	gold quality
apex of heart	UBERON:0002098	61.96	gold quality
prefrontal cortex	UBERON:0000451	61.71	gold quality
islet of Langerhans	UBERON:0000006	61.30	gold quality
gall bladder	UBERON:0002110	61.00	gold quality
lower esophagus	UBERON:0013473	60.75	gold quality
lower esophagus muscularis layer	UBERON:0035833	60.68	gold quality
temporal lobe	UBERON:0001871	60.25	gold quality
amygdala	UBERON:0001876	60.04	gold quality
thoracic aorta	UBERON:0001515	59.86	gold quality
monocyte	CL:0000576	59.83	gold quality
tibial artery	UBERON:0007610	59.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.58

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.