PRADX

Summary

PRADX (PRC2 and DDX5 associated lncRNA, HGNC:40168) is a long non-coding RNA gene on chromosome 11p15.5.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40168
Approved symbol	PRADX
Name	PRC2 and DDX5 associated lncRNA
Location	11p15.5
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235027
Ensembl biotype	lncRNA
Entrez	126568849
RNAcentral	URS000027B716 — lncRNA, 2015 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000449248

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449248 — 2 exons

Exon	Start	End
ENSE00001633782	1761319	1762486
ENSE00001777178	1760348	1761194

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 76.24.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	76.24	gold quality
bone marrow	UBERON:0002371	71.58	gold quality
bone marrow cell	CL:0002092	71.24	gold quality
right adrenal gland cortex	UBERON:0035827	67.45	gold quality
right adrenal gland	UBERON:0001233	67.04	gold quality
left adrenal gland	UBERON:0001234	67.03	gold quality
upper lobe of left lung	UBERON:0008952	66.24	gold quality
left adrenal gland cortex	UBERON:0035825	66.04	gold quality
adrenal gland	UBERON:0002369	65.84	gold quality
sural nerve	UBERON:0015488	65.16	gold quality
lung	UBERON:0002048	64.49	gold quality
cortex of kidney	UBERON:0001225	64.26	gold quality
apex of heart	UBERON:0002098	63.60	gold quality
colonic epithelium	UBERON:0000397	62.82	silver quality
monocyte	CL:0000576	61.81	gold quality
metanephros cortex	UBERON:0010533	61.61	gold quality
spleen	UBERON:0002106	61.56	gold quality
kidney	UBERON:0002113	61.34	gold quality
right lung	UBERON:0002167	61.11	gold quality
skin of leg	UBERON:0001511	60.96	gold quality
skeletal muscle tissue	UBERON:0001134	60.86	gold quality
liver	UBERON:0002107	60.57	gold quality
urinary bladder	UBERON:0001255	60.55	gold quality
lower esophagus mucosa	UBERON:0035834	60.38	gold quality
ganglionic eminence	UBERON:0004023	60.29	gold quality
heart left ventricle	UBERON:0002084	60.08	gold quality
zone of skin	UBERON:0000014	60.03	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.62	gold quality
minor salivary gland	UBERON:0001830	59.37	gold quality
granulocyte	CL:0000094	59.20	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	14.92
E-ANND-3	no	5.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.