PRANCR

Summary

PRANCR (progenitor renewal associated non-coding RNA, HGNC:51126) is a long non-coding RNA gene on chromosome 12q15.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51126
Approved symbol	PRANCR
Name	progenitor renewal associated non-coding RNA
Location	12q15
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257815
Ensembl biotype	lncRNA
OMIM	619085
Entrez	101928062
RNAcentral	URS000075BF57 — lncRNA, 536 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 70 — 70 lncRNA

ENST00000549419, ENST00000549651, ENST00000550216, ENST00000552998, ENST00000553135, ENST00000656495, ENST00000668518, ENST00000670041, ENST00000675475, ENST00000676451, ENST00000686072, ENST00000686629, ENST00000688862, ENST00000689831, ENST00000701750, ENST00000701960, ENST00000807797, ENST00000807798, ENST00000807799, ENST00000807800, ENST00000807801, ENST00000807802, ENST00000807803, ENST00000807804, ENST00000807805, ENST00000807806, ENST00000807807, ENST00000807808, ENST00000807809, ENST00000807810, ENST00000807811, ENST00000807812, ENST00000807813, ENST00000807814, ENST00000807815, ENST00000807816, ENST00000807817, ENST00000807818, ENST00000807819, ENST00000807820, ENST00000807821, ENST00000807822, ENST00000807823, ENST00000807824, ENST00000807825, ENST00000807826, ENST00000807827, ENST00000807828, ENST00000807829, ENST00000807830, ENST00000807831, ENST00000807832, ENST00000807833, ENST00000807834, ENST00000807835, ENST00000807836, ENST00000807837, ENST00000807838, ENST00000807839, ENST00000807840, ENST00000807841, ENST00000807842, ENST00000807843, ENST00000807844, ENST00000807845, ENST00000807846, ENST00000807847, ENST00000807848, ENST00000807849, ENST00000807850

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000549419 — 3 exons

Exon	Start	End
ENSE00002417046	70242797	70242893
ENSE00003861882	69901918	69904419
ENSE00003870223	70243312	70243366

Expression profiles

Bgee: expression breadth ubiquitous, 138 present calls, max score 89.73.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 9.9187 / max 216.1947, expressed in 1754 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
132042	8.5203	1708
132043	1.0365	713
132041	0.2228	90
206795	0.1391	42

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cerebellar hemisphere	UBERON:0002245	89.73	gold quality
right hemisphere of cerebellum	UBERON:0014890	89.69	gold quality
cerebellar cortex	UBERON:0002129	89.67	gold quality
cerebellum	UBERON:0002037	89.58	gold quality
thymus	UBERON:0002370	88.65	gold quality
pituitary gland	UBERON:0000007	88.49	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.44	gold quality
cerebellar vermis	UBERON:0004720	88.00	gold quality
monocyte	CL:0000576	87.43	gold quality
adenohypophysis	UBERON:0002196	86.98	gold quality
leukocyte	CL:0000738	86.90	gold quality
right uterine tube	UBERON:0001302	86.29	gold quality
granulocyte	CL:0000094	85.47	gold quality
right testis	UBERON:0004534	84.78	gold quality
left testis	UBERON:0004533	84.55	gold quality
testis	UBERON:0000473	84.12	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.03	gold quality
spleen	UBERON:0002106	83.87	gold quality
right lobe of thyroid gland	UBERON:0001119	83.47	gold quality
left lobe of thyroid gland	UBERON:0001120	83.45	gold quality
thyroid gland	UBERON:0002046	83.32	gold quality
mucosa of transverse colon	UBERON:0004991	83.08	gold quality
lower esophagus mucosa	UBERON:0035834	82.96	gold quality
metanephros cortex	UBERON:0010533	82.17	gold quality
popliteal artery	UBERON:0002250	82.11	gold quality
tibial artery	UBERON:0007610	82.10	gold quality
tibial nerve	UBERON:0001323	82.05	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	81.84	gold quality
prostate gland	UBERON:0002367	81.39	gold quality
cortex of kidney	UBERON:0001225	81.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.81

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• The Long Noncoding RNA PRANCR Is Associated with Alternative Splicing of Fibronectin-1 in Keratinocytes. (PMID:36906126)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.