PRC1-AS1

Summary

PRC1-AS1 (PRC1 antisense RNA 1, HGNC:48587) is a long non-coding RNA gene on chromosome 15q26.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48587
Approved symbol	PRC1-AS1
Name	PRC1 antisense RNA 1
Location	15q26.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258725
Ensembl biotype	lncRNA
Entrez	100507118
RNAcentral	URS000075EDB1 — lncRNA, 1528 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000554388, ENST00000556200, ENST00000654370, ENST00000656754, ENST00000657141, ENST00000660154

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000554388 — 4 exons

Exon	Start	End
ENSE00002458473	90983692	90983778
ENSE00002482127	90987630	90988625
ENSE00002507703	90966340	90966678
ENSE00002531952	90981955	90982090

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 88.46.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0497 / max 41.0487, expressed in 6 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
148540	0.0341	3
148538	0.0089	5
148539	0.0066	3

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	88.46	gold quality
right testis	UBERON:0004534	88.23	gold quality
testis	UBERON:0000473	87.69	gold quality
cerebellar hemisphere	UBERON:0002245	84.48	gold quality
cerebellar cortex	UBERON:0002129	84.47	gold quality
right hemisphere of cerebellum	UBERON:0014890	84.34	gold quality
cerebellum	UBERON:0002037	84.32	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.39	gold quality
bone marrow	UBERON:0002371	80.99	gold quality
bone marrow cell	CL:0002092	80.73	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.25	gold quality
superior frontal gyrus	UBERON:0002661	74.86	gold quality
right frontal lobe	UBERON:0002810	73.64	gold quality
primary visual cortex	UBERON:0002436	73.24	gold quality
Brodmann (1909) area 9	UBERON:0013540	72.06	gold quality
sural nerve	UBERON:0015488	72.03	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	71.79	gold quality
cortical plate	UBERON:0005343	71.68	gold quality
ventricular zone	UBERON:0003053	70.93	gold quality
frontal cortex	UBERON:0001870	69.97	gold quality
colonic epithelium	UBERON:0000397	69.96	gold quality
right uterine tube	UBERON:0001302	69.95	gold quality
nucleus accumbens	UBERON:0001882	69.92	gold quality
anterior cingulate cortex	UBERON:0009835	69.84	gold quality
cerebral cortex	UBERON:0000956	69.83	gold quality
brain	UBERON:0000955	69.66	gold quality
ganglionic eminence	UBERON:0004023	69.56	gold quality
mucosa of stomach	UBERON:0001199	69.32	gold quality
skin of leg	UBERON:0001511	68.59	gold quality
zone of skin	UBERON:0000014	68.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.