PRDM4-AS1

Summary

PRDM4-AS1 (PRDM4 antisense RNA 1, HGNC:56186) is a long non-coding RNA gene on chromosome 12q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56186
Approved symbol	PRDM4-AS1
Name	PRDM4 antisense RNA 1
Location	12q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258136
Ensembl biotype	lncRNA
Entrez	101929162
RNAcentral	URS0000759A13 — lncRNA, 1714 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000546714, ENST00000546829

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546714 — 5 exons

Exon	Start	End
ENSE00002335341	107738022	107738489
ENSE00002335505	107758275	107758392
ENSE00002378948	107759772	107759968
ENSE00002387922	107739127	107739664
ENSE00002429564	107736589	107736947

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 85.14.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.14	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.12	gold quality
sperm	CL:0000019	71.55	silver quality
bone marrow cell	CL:0002092	66.85	silver quality
colonic epithelium	UBERON:0000397	66.18	silver quality
left testis	UBERON:0004533	63.90	gold quality
right testis	UBERON:0004534	63.46	gold quality
lower esophagus mucosa	UBERON:0035834	63.46	gold quality
testis	UBERON:0000473	62.55	gold quality
stromal cell of endometrium	CL:0002255	62.32	gold quality
ventricular zone	UBERON:0003053	62.26	gold quality
adrenal tissue	UBERON:0018303	60.62	gold quality
rectum	UBERON:0001052	60.51	gold quality
granulocyte	CL:0000094	60.21	gold quality
esophagus mucosa	UBERON:0002469	59.34	gold quality
small intestine Peyer’s patch	UBERON:0003454	59.33	gold quality
apex of heart	UBERON:0002098	59.17	gold quality
ganglionic eminence	UBERON:0004023	59.06	gold quality
right adrenal gland cortex	UBERON:0035827	58.67	gold quality
small intestine	UBERON:0002108	57.93	gold quality
right adrenal gland	UBERON:0001233	57.91	gold quality
leukocyte	CL:0000738	57.69	gold quality
transverse colon	UBERON:0001157	57.55	gold quality
body of pancreas	UBERON:0001150	57.45	gold quality
monocyte	CL:0000576	57.34	gold quality
left adrenal gland cortex	UBERON:0035825	57.33	gold quality
esophagus	UBERON:0001043	57.21	gold quality
metanephros cortex	UBERON:0010533	57.11	gold quality
left adrenal gland	UBERON:0001234	57.03	gold quality
vermiform appendix	UBERON:0001154	56.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.