PRDM8-AS1

Summary

PRDM8-AS1 (PRDM8 antisense RNA 1, HGNC:55581) is a long non-coding RNA gene on chromosome 4q21.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55581
Approved symbol	PRDM8-AS1
Name	PRDM8 antisense RNA 1
Location	4q21.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248719
Ensembl biotype	lncRNA
Entrez	105377303
RNAcentral	URS00026A23DF — lncRNA, 2957 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000503589, ENST00000653209, ENST00000813820, ENST00000813821, ENST00000813822, ENST00000813823, ENST00000813824, ENST00000813825, ENST00000813826

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503589 — 2 exons

Exon	Start	End
ENSE00002085016	80189749	80190169
ENSE00002087072	80183280	80183424

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 96.96.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.96	silver quality
cortical plate	UBERON:0005343	74.74	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.31	gold quality
bone marrow cell	CL:0002092	66.03	silver quality
colonic epithelium	UBERON:0000397	65.32	silver quality
stromal cell of endometrium	CL:0002255	65.09	gold quality
prostate gland	UBERON:0002367	64.03	gold quality
ganglionic eminence	UBERON:0004023	63.16	gold quality
substantia nigra	UBERON:0002038	63.00	gold quality
mucosa of stomach	UBERON:0001199	62.09	gold quality
Ammon’s horn	UBERON:0001954	61.78	gold quality
primary visual cortex	UBERON:0002436	61.76	gold quality
bone marrow	UBERON:0002371	61.75	gold quality
ventricular zone	UBERON:0003053	61.67	gold quality
corpus callosum	UBERON:0002336	61.56	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	61.55	gold quality
lower esophagus muscularis layer	UBERON:0035833	61.26	gold quality
lower esophagus	UBERON:0013473	61.20	gold quality
prefrontal cortex	UBERON:0000451	60.22	gold quality
vermiform appendix	UBERON:0001154	59.86	gold quality
blood	UBERON:0000178	59.53	gold quality
Brodmann (1909) area 9	UBERON:0013540	59.51	gold quality
frontal cortex	UBERON:0001870	59.11	gold quality
cerebral cortex	UBERON:0000956	58.54	gold quality
amygdala	UBERON:0001876	58.49	gold quality
temporal lobe	UBERON:0001871	58.41	gold quality
muscle layer of sigmoid colon	UBERON:0035805	57.95	gold quality
myometrium	UBERON:0001296	57.94	gold quality
right frontal lobe	UBERON:0002810	57.91	gold quality
hypothalamus	UBERON:0001898	57.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.