PRDX6-AS1

Summary

PRDX6-AS1 (PRDX6 antisense RNA 1, HGNC:54870) is a long non-coding RNA gene on chromosome 1q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54870
Approved symbol	PRDX6-AS1
Name	PRDX6 antisense RNA 1
Location	1q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000203739
Ensembl biotype	lncRNA
Entrez	101928673
RNAcentral	URS00007E3E18 — lncRNA, 1835 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000367716, ENST00000437190, ENST00000654140, ENST00000654650, ENST00000659863, ENST00000660739, ENST00000661092, ENST00000661267, ENST00000669220, ENST00000688677, ENST00000702826, ENST00000778745, ENST00000778746, ENST00000778747, ENST00000778748

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000367716 — 2 exons

Exon	Start	End
ENSE00001445480	173460378	173461362
ENSE00001594649	173417793	173418622

Expression profiles

Bgee: expression breadth ubiquitous, 171 present calls, max score 86.57.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.0348 / max 84.4849, expressed in 1516 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
15947	3.2526	1088
15948	1.7822	997

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.57	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.94	gold quality
mucosa of stomach	UBERON:0001199	81.89	gold quality
bone marrow cell	CL:0002092	79.00	gold quality
blood	UBERON:0000178	78.64	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	77.98	gold quality
gastrocnemius	UBERON:0001388	77.45	gold quality
muscle of leg	UBERON:0001383	76.91	gold quality
lower esophagus muscularis layer	UBERON:0035833	76.38	gold quality
mucosa of transverse colon	UBERON:0004991	76.34	gold quality
lower esophagus	UBERON:0013473	76.32	gold quality
granulocyte	CL:0000094	76.11	gold quality
corpus callosum	UBERON:0002336	76.11	gold quality
body of pancreas	UBERON:0001150	75.63	gold quality
calcaneal tendon	UBERON:0003701	75.16	gold quality
right lobe of liver	UBERON:0001114	75.04	gold quality
sural nerve	UBERON:0015488	74.75	gold quality
colonic epithelium	UBERON:0000397	74.57	gold quality
ectocervix	UBERON:0012249	74.52	gold quality
transverse colon	UBERON:0001157	74.50	gold quality
right lung	UBERON:0002167	74.30	gold quality
monocyte	CL:0000576	74.05	gold quality
leukocyte	CL:0000738	74.01	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.00	gold quality
tibial nerve	UBERON:0001323	73.89	gold quality
descending thoracic aorta	UBERON:0002345	73.85	gold quality
pancreatic ductal cell	CL:0002079	73.73	silver quality
left uterine tube	UBERON:0001303	73.73	gold quality
omental fat pad	UBERON:0010414	73.56	gold quality
peritoneum	UBERON:0002358	73.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.70

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• PRDX6 AS1 gene polymorphisms and SLE susceptibility in Chinese populations. (PMID:36311744)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.