PREP-AS1

Summary

PREP-AS1 (PREP antisense RNA 1, HGNC:40466) is a long non-coding RNA gene on chromosome 6q21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40466
Approved symbol	PREP-AS1
Name	PREP antisense RNA 1
Location	6q21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231628
Ensembl biotype	lncRNA
Entrez	139355238
RNAcentral	URS000060186D — lncRNA, 1198 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000452363

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000452363 — 2 exons

Exon	Start	End
ENSE00001748593	105280621	105281755
ENSE00001777812	105279016	105279078

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 89.07.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
gastrocnemius	UBERON:0001388	89.07	gold quality
muscle of leg	UBERON:0001383	86.84	gold quality
skeletal muscle tissue	UBERON:0001134	81.74	gold quality
hindlimb stylopod muscle	UBERON:0004252	80.19	gold quality
bone marrow	UBERON:0002371	74.28	gold quality
monocyte	CL:0000576	73.56	gold quality
bone marrow cell	CL:0002092	73.35	silver quality
leukocyte	CL:0000738	72.60	gold quality
rectum	UBERON:0001052	72.08	gold quality
sural nerve	UBERON:0015488	71.68	silver quality
transverse colon	UBERON:0001157	68.25	gold quality
colonic epithelium	UBERON:0000397	66.74	silver quality
right lung	UBERON:0002167	66.47	gold quality
endometrium	UBERON:0001295	66.38	gold quality
skin of abdomen	UBERON:0001416	66.38	gold quality
small intestine Peyer’s patch	UBERON:0003454	66.33	gold quality
small intestine	UBERON:0002108	66.25	gold quality
zone of skin	UBERON:0000014	66.03	gold quality
skin of leg	UBERON:0001511	65.87	gold quality
upper lobe of left lung	UBERON:0008952	65.82	gold quality
subcutaneous adipose tissue	UBERON:0002190	65.68	gold quality
body of pancreas	UBERON:0001150	65.65	gold quality
right ovary	UBERON:0002118	65.64	gold quality
endocervix	UBERON:0000458	65.61	gold quality
intestine	UBERON:0000160	65.43	gold quality
uterine cervix	UBERON:0000002	65.39	gold quality
granulocyte	CL:0000094	65.31	gold quality
colon	UBERON:0001155	65.25	gold quality
smooth muscle tissue	UBERON:0001135	65.21	gold quality
ectocervix	UBERON:0012249	64.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.