PRICKLE1-AS1

Summary

PRICKLE1-AS1 (PRICKLE1 antisense RNA 1, HGNC:58444) is a long non-coding RNA gene on chromosome 12q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58444
Approved symbol	PRICKLE1-AS1
Name	PRICKLE1 antisense RNA 1
Location	12q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257225
Ensembl biotype	lncRNA
Entrez	141858805

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000547824

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000547824 — 2 exons

Exon	Start	End
ENSE00002353374	42464701	42466128
ENSE00002420883	42459366	42460728

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 83.16.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.16	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.98	silver quality
sural nerve	UBERON:0015488	64.06	gold quality
cortical plate	UBERON:0005343	62.81	gold quality
ganglionic eminence	UBERON:0004023	62.27	gold quality
ventricular zone	UBERON:0003053	61.13	gold quality
cerebellum	UBERON:0002037	57.30	gold quality
cerebellar cortex	UBERON:0002129	57.30	gold quality
cerebellar hemisphere	UBERON:0002245	57.26	gold quality
right hemisphere of cerebellum	UBERON:0014890	56.99	gold quality
adrenal tissue	UBERON:0018303	56.74	gold quality
right lobe of liver	UBERON:0001114	56.10	gold quality
leukocyte	CL:0000738	53.89	gold quality
liver	UBERON:0002107	53.41	gold quality
hindlimb stylopod muscle	UBERON:0004252	52.64	silver quality
skeletal muscle tissue	UBERON:0001134	52.50	silver quality
granulocyte	CL:0000094	52.48	gold quality
monocyte	CL:0000576	52.11	gold quality
lymph node	UBERON:0000029	51.16	gold quality
blood	UBERON:0000178	51.12	silver quality
endometrium	UBERON:0001295	50.21	gold quality
muscle of leg	UBERON:0001383	49.76	gold quality
islet of Langerhans	UBERON:0000006	49.65	gold quality
primary visual cortex	UBERON:0002436	49.62	gold quality
gastrocnemius	UBERON:0001388	49.27	gold quality
myometrium	UBERON:0001296	48.96	gold quality
spleen	UBERON:0002106	48.90	gold quality
kidney	UBERON:0002113	48.83	gold quality
right coronary artery	UBERON:0001625	48.70	gold quality
calcaneal tendon	UBERON:0003701	48.66	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.