PRICKLE2-DT

Summary

PRICKLE2-DT (PRICKLE2 divergent transcript, HGNC:52829) is a long non-coding RNA gene on chromosome 3p14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52829
Approved symbol	PRICKLE2-DT
Name	PRICKLE2 divergent transcript
Location	3p14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244564
Ensembl biotype	lncRNA
Entrez	101929316
RNAcentral	URS00026A283B — lncRNA, 1777 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000487097, ENST00000659263, ENST00000762005, ENST00000762006

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000487097 — 4 exons

Exon	Start	End
ENSE00001822129	64454737	64454832
ENSE00001834539	64450514	64450631
ENSE00001855077	64448523	64448696
ENSE00001934758	64445231	64445407

Expression profiles

Bgee: expression breadth broad, 75 present calls, max score 92.20.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0053 / max 4.7244, expressed in 2 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
202801	0.0053	2

Top tissues by expression

75 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.20	gold quality
left testis	UBERON:0004533	75.18	gold quality
testis	UBERON:0000473	74.94	gold quality
right testis	UBERON:0004534	73.26	gold quality
endometrium	UBERON:0001295	66.13	gold quality
body of uterus	UBERON:0009853	65.81	gold quality
sural nerve	UBERON:0015488	62.16	silver quality
multicellular organism	UBERON:0000468	58.31	gold quality
small intestine	UBERON:0002108	55.77	gold quality
monocyte	CL:0000576	55.35	gold quality
smooth muscle tissue	UBERON:0001135	55.00	gold quality
myometrium	UBERON:0001296	54.74	gold quality
gastrocnemius	UBERON:0001388	53.34	gold quality
duodenum	UBERON:0002114	53.26	gold quality
muscle of leg	UBERON:0001383	53.18	gold quality
islet of Langerhans	UBERON:0000006	51.56	gold quality
skin of leg	UBERON:0001511	51.08	gold quality
placenta	UBERON:0001987	50.30	gold quality
tibial nerve	UBERON:0001323	49.56	gold quality
pancreas	UBERON:0001264	49.33	gold quality
kidney	UBERON:0002113	49.31	gold quality
fallopian tube	UBERON:0003889	49.30	gold quality
gall bladder	UBERON:0002110	49.22	gold quality
ovary	UBERON:0000992	48.50	gold quality
adult mammalian kidney	UBERON:0000082	48.19	gold quality
right ovary	UBERON:0002118	48.16	gold quality
prefrontal cortex	UBERON:0000451	47.75	silver quality
blood	UBERON:0000178	47.00	silver quality
rectum	UBERON:0001052	46.93	gold quality
left ovary	UBERON:0002119	46.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.66

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.