PRKAB1-AS1

Summary

PRKAB1-AS1 (PRKAB1, TMEM233 and CCDC60 antisense RNA 1, HGNC:58183) is a long non-coding RNA gene on chromosome 12q24.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58183
Approved symbol	PRKAB1-AS1
Name	PRKAB1, TMEM233 and CCDC60 antisense RNA 1
Location	12q24.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248636
Ensembl biotype	lncRNA
Entrez	105370027
RNAcentral	URS00026A1CC3 — lncRNA, 1166 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000509470, ENST00000535511, ENST00000537366, ENST00000665601, ENST00000815425, ENST00000815426, ENST00000815427, ENST00000815428, ENST00000815429, ENST00000815430, ENST00000815431, ENST00000815432, ENST00000815433

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000509470 — 3 exons

Exon	Start	End
ENSE00002023013	119387991	119388267
ENSE00002034977	119594182	119594501
ENSE00002063938	119553548	119553645

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 91.46.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.46	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.42	gold quality
muscle of leg	UBERON:0001383	80.55	gold quality
gastrocnemius	UBERON:0001388	80.04	gold quality
hindlimb stylopod muscle	UBERON:0004252	76.90	gold quality
monocyte	CL:0000576	73.51	gold quality
sural nerve	UBERON:0015488	73.18	silver quality
leukocyte	CL:0000738	72.82	gold quality
left lobe of thyroid gland	UBERON:0001120	72.58	gold quality
right lobe of thyroid gland	UBERON:0001119	71.89	gold quality
thyroid gland	UBERON:0002046	71.33	gold quality
spleen	UBERON:0002106	70.92	gold quality
bone marrow cell	CL:0002092	70.30	silver quality
adult mammalian kidney	UBERON:0000082	69.20	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	68.67	gold quality
anterior cingulate cortex	UBERON:0009835	68.67	gold quality
prefrontal cortex	UBERON:0000451	68.66	gold quality
right lung	UBERON:0002167	68.24	gold quality
left adrenal gland	UBERON:0001234	68.02	gold quality
amygdala	UBERON:0001876	67.16	gold quality
left adrenal gland cortex	UBERON:0035825	67.09	gold quality
sperm	CL:0000019	67.04	silver quality
right adrenal gland	UBERON:0001233	66.90	gold quality
vastus lateralis	UBERON:0001379	66.69	gold quality
quadriceps femoris	UBERON:0001377	66.40	gold quality
granulocyte	CL:0000094	66.23	gold quality
upper lobe of left lung	UBERON:0008952	66.00	gold quality
adrenal gland	UBERON:0002369	65.77	gold quality
metanephros cortex	UBERON:0010533	65.71	gold quality
apex of heart	UBERON:0002098	65.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.