PRKAG2-AS1

Summary

PRKAG2-AS1 (PRKAG2 antisense RNA 1, HGNC:40468) is a long non-coding RNA gene on chromosome 7q36.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40468
Approved symbol	PRKAG2-AS1
Name	PRKAG2 antisense RNA 1
Location	7q36.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000239911
Ensembl biotype	lncRNA
Entrez	100505483
RNAcentral	URS000075E0AB — lncRNA, 808 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000464464, ENST00000467458, ENST00000687407, ENST00000689578, ENST00000690829, ENST00000702909, ENST00000765304, ENST00000793803

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000464464 — 3 exons

Exon	Start	End
ENSE00001813861	151878562	151878814
ENSE00001824785	151877042	151877140
ENSE00001876759	151877837	151877866

Expression profiles

Bgee: expression breadth ubiquitous, 217 present calls, max score 93.26.

FANTOM5 (CAGE): breadth broad, TPM avg 4.4389 / max 96.7332, expressed in 890 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
82112	3.0923	822
82113	0.4315	228
82114	0.3576	149
82110	0.3087	185
82111	0.2487	141

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
Brodmann (1909) area 23	UBERON:0013554	93.26	gold quality
middle temporal gyrus	UBERON:0002771	92.57	gold quality
endothelial cell	CL:0000115	92.07	gold quality
primary visual cortex	UBERON:0002436	90.31	gold quality
prefrontal cortex	UBERON:0000451	89.03	gold quality
anterior cingulate cortex	UBERON:0009835	88.76	gold quality
Brodmann (1909) area 9	UBERON:0013540	88.74	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	88.40	gold quality
occipital lobe	UBERON:0002021	88.11	gold quality
lateral nuclear group of thalamus	UBERON:0002736	87.72	gold quality
neocortex	UBERON:0001950	87.48	gold quality
frontal cortex	UBERON:0001870	87.40	gold quality
cerebral cortex	UBERON:0000956	86.65	gold quality
right frontal lobe	UBERON:0002810	86.29	gold quality
superior frontal gyrus	UBERON:0002661	85.94	gold quality
amygdala	UBERON:0001876	84.92	gold quality
Ammon’s horn	UBERON:0001954	84.33	gold quality
temporal lobe	UBERON:0001871	84.24	gold quality
right lobe of liver	UBERON:0001114	84.18	gold quality
postcentral gyrus	UBERON:0002581	83.81	gold quality
parietal lobe	UBERON:0001872	83.58	gold quality
monocyte	CL:0000576	83.42	gold quality
leukocyte	CL:0000738	82.91	gold quality
entorhinal cortex	UBERON:0002728	82.88	gold quality
pons	UBERON:0000988	82.46	gold quality
forebrain	UBERON:0001890	81.84	gold quality
Brodmann (1909) area 46	UBERON:0006483	81.74	gold quality
hypothalamus	UBERON:0001898	81.28	gold quality
granulocyte	CL:0000094	81.15	gold quality
adipose tissue	UBERON:0001013	80.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.95

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Identification of long non-coding RNAs in advanced prostate cancer associated with androgen receptor splicing factors. (PMID:32704143)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.