PRKAR1B-AS1

Summary

PRKAR1B-AS1 (PRKAR1B antisense RNA 1, HGNC:40470) is a long non-coding RNA gene on chromosome 7p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40470
Approved symbol	PRKAR1B-AS1
Name	PRKAR1B antisense RNA 1
Location	7p22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237181
Ensembl biotype	lncRNA
Entrez	101926963
RNAcentral	URS000075A91B — lncRNA, 1107 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000429872, ENST00000749497, ENST00000749498, ENST00000749499, ENST00000749500, ENST00000749501

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429872 — 2 exons

Exon	Start	End
ENSE00003987598	602792	603297
ENSE00004093204	607865	608500

Expression profiles

Bgee: expression breadth ubiquitous, 155 present calls, max score 84.43.

FANTOM5 (CAGE): breadth broad, TPM avg 1.6765 / max 114.7063, expressed in 332 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76863	0.6576	242
76862	0.3815	126
76861	0.3051	103
76864	0.2665	96
76865	0.0658	35

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	84.43	gold quality
monocyte	CL:0000576	83.62	gold quality
leukocyte	CL:0000738	83.17	gold quality
right coronary artery	UBERON:0001625	79.16	gold quality
left coronary artery	UBERON:0001626	77.76	gold quality
spleen	UBERON:0002106	77.62	gold quality
coronary artery	UBERON:0001621	76.11	gold quality
ascending aorta	UBERON:0001496	76.08	gold quality
blood	UBERON:0000178	76.04	gold quality
thoracic aorta	UBERON:0001515	76.04	gold quality
vermiform appendix	UBERON:0001154	75.20	gold quality
buccal mucosa cell	CL:0002336	75.11	gold quality
descending thoracic aorta	UBERON:0002345	75.10	gold quality
right lung	UBERON:0002167	74.81	gold quality
aorta	UBERON:0000947	73.61	gold quality
lymph node	UBERON:0000029	73.52	gold quality
bone marrow cell	CL:0002092	72.78	gold quality
cartilage tissue	UBERON:0002418	72.29	silver quality
upper lobe of left lung	UBERON:0008952	72.28	gold quality
popliteal artery	UBERON:0002250	72.06	gold quality
tibial artery	UBERON:0007610	72.06	gold quality
upper lobe of lung	UBERON:0008948	70.70	gold quality
tendon of biceps brachii	UBERON:0008188	70.22	gold quality
gastrocnemius	UBERON:0001388	69.80	gold quality
omental fat pad	UBERON:0010414	69.74	gold quality
peritoneum	UBERON:0002358	69.66	gold quality
muscle of leg	UBERON:0001383	69.34	gold quality
small intestine Peyer’s patch	UBERON:0003454	69.15	gold quality
adipose tissue of abdominal region	UBERON:0007808	68.97	gold quality
caecum	UBERON:0001153	68.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.91

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.