PRKAR2A-AS1

Summary

PRKAR2A-AS1 (PRKAR2A antisense RNA 1, HGNC:40471) is a long non-coding RNA gene on chromosome 3p21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40471
Approved symbol	PRKAR2A-AS1
Name	PRKAR2A antisense RNA 1
Location	3p21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224424
Ensembl biotype	lncRNA
Entrez	100506637
RNAcentral	URS000075CD16 — lncRNA, 3485 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000412171, ENST00000416209, ENST00000431705, ENST00000435419, ENST00000655796, ENST00000665061, ENST00000669166, ENST00000721545, ENST00000721546, ENST00000721547, ENST00000721548

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412171 — 2 exons

Exon	Start	End
ENSE00001700693	48848987	48849454
ENSE00001874020	48847937	48848408

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 79.68.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4039 / max 17.1412, expressed in 199 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
36587	0.4039	199

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	79.68	gold quality
right testis	UBERON:0004534	79.58	gold quality
testis	UBERON:0000473	78.95	gold quality
sural nerve	UBERON:0015488	71.93	silver quality
islet of Langerhans	UBERON:0000006	70.12	gold quality
skeletal muscle tissue	UBERON:0001134	68.14	gold quality
bone marrow cell	CL:0002092	67.02	silver quality
stromal cell of endometrium	CL:0002255	65.44	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	65.34	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.30	gold quality
muscle of leg	UBERON:0001383	65.01	gold quality
gastrocnemius	UBERON:0001388	64.79	gold quality
corpus callosum	UBERON:0002336	64.59	gold quality
muscle tissue	UBERON:0002385	64.49	gold quality
prefrontal cortex	UBERON:0000451	64.45	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.01	gold quality
right adrenal gland	UBERON:0001233	63.42	gold quality
right adrenal gland cortex	UBERON:0035827	63.30	gold quality
substantia nigra	UBERON:0002038	62.60	gold quality
frontal cortex	UBERON:0001870	62.31	gold quality
left adrenal gland	UBERON:0001234	62.29	gold quality
pituitary gland	UBERON:0000007	62.01	gold quality
adenohypophysis	UBERON:0002196	61.85	gold quality
left adrenal gland cortex	UBERON:0035825	61.82	gold quality
adrenal gland	UBERON:0002369	61.79	gold quality
apex of heart	UBERON:0002098	61.70	gold quality
ventricular zone	UBERON:0003053	61.68	gold quality
blood	UBERON:0000178	61.24	gold quality
temporal lobe	UBERON:0001871	61.02	gold quality
cortical plate	UBERON:0005343	61.01	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.