PRKAR2B-AS1

Summary

PRKAR2B-AS1 (PRKAR2B antisense RNA 1, HGNC:40472) is a long non-coding RNA gene on chromosome 7q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40472
Approved symbol	PRKAR2B-AS1
Name	PRKAR2B antisense RNA 1
Location	7q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243193
Ensembl biotype	lncRNA
Entrez	105375441
RNAcentral	URS0002A60477 — lncRNA, 913 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 7 lncRNA, 1 retained_intron

ENST00000494849, ENST00000589433, ENST00000626365, ENST00000627539, ENST00000629022, ENST00000631092, ENST00000825005, ENST00000825006

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000494849 — 3 exons

Exon	Start	End
ENSE00001860867	107133604	107133733
ENSE00001873098	107129034	107129085
ENSE00001954385	107077226	107077385

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 89.85.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0517 / max 6.7763, expressed in 26 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
85593	0.0517	26

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	89.85	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.81	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.90	gold quality
sural nerve	UBERON:0015488	75.18	gold quality
corpus callosum	UBERON:0002336	74.96	gold quality
bone marrow cell	CL:0002092	70.78	gold quality
colonic epithelium	UBERON:0000397	69.40	gold quality
ganglionic eminence	UBERON:0004023	68.17	gold quality
cortical plate	UBERON:0005343	67.49	gold quality
ventricular zone	UBERON:0003053	66.90	gold quality
spleen	UBERON:0002106	65.99	gold quality
mucosa of stomach	UBERON:0001199	65.96	gold quality
adrenal gland	UBERON:0002369	64.96	gold quality
bone marrow	UBERON:0002371	64.94	gold quality
stromal cell of endometrium	CL:0002255	64.38	gold quality
left adrenal gland cortex	UBERON:0035825	63.98	gold quality
right adrenal gland	UBERON:0001233	63.69	gold quality
right adrenal gland cortex	UBERON:0035827	63.66	gold quality
primary visual cortex	UBERON:0002436	63.62	gold quality
calcaneal tendon	UBERON:0003701	63.23	gold quality
left adrenal gland	UBERON:0001234	62.87	gold quality
ovary	UBERON:0000992	62.46	gold quality
left ovary	UBERON:0002119	62.22	gold quality
monocyte	CL:0000576	61.30	gold quality
leukocyte	CL:0000738	60.92	gold quality
right ovary	UBERON:0002118	60.82	gold quality
skeletal muscle tissue	UBERON:0001134	59.69	gold quality
subcutaneous adipose tissue	UBERON:0002190	59.43	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.22	gold quality
liver	UBERON:0002107	58.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	5.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.