PRKCE-AS1

Summary

PRKCE-AS1 (PRKCE antisense RNA 1, HGNC:40474) is a long non-coding RNA gene on chromosome 2p21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40474
Approved symbol	PRKCE-AS1
Name	PRKCE antisense RNA 1
Location	2p21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228481
Ensembl biotype	lncRNA
Entrez	105374580
RNAcentral	URS0000362203 — lncRNA, 374 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000423120

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000423120 — 2 exons

Exon	Start	End
ENSE00001741782	45674701	45674907
ENSE00001778885	45675310	45675476

Expression profiles

Bgee: expression breadth ubiquitous, 107 present calls, max score 92.16.

Top tissues by expression

107 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.16	gold quality
colonic epithelium	UBERON:0000397	78.75	gold quality
tonsil	UBERON:0002372	71.24	gold quality
bone marrow cell	CL:0002092	70.40	silver quality
corpus callosum	UBERON:0002336	69.75	gold quality
liver	UBERON:0002107	68.40	gold quality
skeletal muscle tissue	UBERON:0001134	67.91	silver quality
lymph node	UBERON:0000029	66.53	gold quality
gall bladder	UBERON:0002110	64.02	gold quality
monocyte	CL:0000576	62.94	gold quality
calcaneal tendon	UBERON:0003701	62.67	gold quality
bone marrow	UBERON:0002371	62.11	gold quality
sural nerve	UBERON:0015488	62.07	gold quality
kidney	UBERON:0002113	61.84	gold quality
superior frontal gyrus	UBERON:0002661	61.02	gold quality
adult mammalian kidney	UBERON:0000082	60.61	gold quality
primary visual cortex	UBERON:0002436	60.41	gold quality
urinary bladder	UBERON:0001255	60.27	gold quality
blood	UBERON:0000178	59.66	gold quality
adrenal tissue	UBERON:0018303	59.05	gold quality
stomach	UBERON:0000945	58.15	gold quality
right lobe of liver	UBERON:0001114	57.94	gold quality
islet of Langerhans	UBERON:0000006	56.51	gold quality
lung	UBERON:0002048	54.46	gold quality
uterine cervix	UBERON:0000002	54.29	silver quality
gastrocnemius	UBERON:0001388	54.17	gold quality
pancreas	UBERON:0001264	54.01	gold quality
adrenal gland	UBERON:0002369	53.50	gold quality
prefrontal cortex	UBERON:0000451	53.17	gold quality
myometrium	UBERON:0001296	52.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.