PRKCH-AS2

Summary

PRKCH-AS2 (PRKCH antisense RNA 2, HGNC:58291) is a long non-coding RNA gene on chromosome 14q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58291
Approved symbol	PRKCH-AS2
Name	PRKCH antisense RNA 2
Location	14q23.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258926
Ensembl biotype	lncRNA
Entrez	105370525
RNAcentral	URS00026A1A1B — lncRNA, 2925 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000556543, ENST00000654868, ENST00000655460, ENST00000657299, ENST00000657687, ENST00000660507, ENST00000666850

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000556543 — 2 exons

Exon	Start	End
ENSE00002464234	61537508	61537906
ENSE00002518834	61545094	61545287

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 74.86.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	74.86	gold quality
substantia nigra	UBERON:0002038	73.34	gold quality
bone marrow cell	CL:0002092	72.70	gold quality
right lobe of thyroid gland	UBERON:0001119	70.85	gold quality
bone marrow	UBERON:0002371	69.83	gold quality
left lobe of thyroid gland	UBERON:0001120	69.57	gold quality
thyroid gland	UBERON:0002046	69.28	gold quality
hypothalamus	UBERON:0001898	68.23	gold quality
putamen	UBERON:0001874	67.56	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	67.37	gold quality
caudate nucleus	UBERON:0001873	67.25	gold quality
tonsil	UBERON:0002372	66.55	gold quality
blood	UBERON:0000178	66.39	gold quality
sural nerve	UBERON:0015488	66.27	silver quality
amygdala	UBERON:0001876	63.22	gold quality
temporal lobe	UBERON:0001871	63.16	gold quality
nucleus accumbens	UBERON:0001882	63.11	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.00	gold quality
cerebellum	UBERON:0002037	62.63	gold quality
cerebellar cortex	UBERON:0002129	62.59	gold quality
cerebellar hemisphere	UBERON:0002245	62.59	gold quality
skeletal muscle tissue	UBERON:0001134	62.55	gold quality
lymph node	UBERON:0000029	61.91	gold quality
upper lobe of left lung	UBERON:0008952	61.33	gold quality
lung	UBERON:0002048	60.96	gold quality
cortical plate	UBERON:0005343	60.64	gold quality
calcaneal tendon	UBERON:0003701	60.63	gold quality
brain	UBERON:0000955	60.34	gold quality
lower esophagus mucosa	UBERON:0035834	60.26	gold quality
granulocyte	CL:0000094	60.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.