PRKCQ-AS1

Summary

PRKCQ-AS1 (PRKCQ antisense RNA 1, HGNC:44689) is a long non-coding RNA gene on chromosome 10p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44689
Approved symbol	PRKCQ-AS1
Name	PRKCQ antisense RNA 1
Location	10p14
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000414894.1
Ensembl gene	ENSG00000237943
Ensembl biotype	lncRNA
Entrez	439949
RNAcentral	URS000075C045 — lncRNA, 2253 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 26 — 25 lncRNA, 1 retained_intron

ENST00000414894, ENST00000445427, ENST00000449648, ENST00000455810, ENST00000561822, ENST00000607982, ENST00000607996, ENST00000608453, ENST00000608526, ENST00000609346, ENST00000609627, ENST00000613651, ENST00000613985, ENST00000615210, ENST00000623015, ENST00000623160, ENST00000624678, ENST00000624974, ENST00000625102, ENST00000625147, ENST00000663449, ENST00000667092, ENST00000667809, ENST00000687343, ENST00000688479, ENST00000702326

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414894 — 2 exons

Exon	Start	End
ENSE00001617358	6583676	6583918
ENSE00001770793	6585558	6585679

Expression profiles

Bgee: expression breadth ubiquitous, 199 present calls, max score 94.10.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 12.0193 / max 761.4277, expressed in 922 samples.

FANTOM5 promoters (12 alternative TSS)

Promoter ID	TPM avg	Samples expressed
103708	3.8653	654
103714	2.4026	97
103706	2.1490	655
103713	1.7849	105
103715	0.6150	65
103707	0.4500	217
103709	0.1773	102
103710	0.1715	99
205718	0.1443	51
103711	0.0958	51

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	94.10	gold quality
hindlimb stylopod muscle	UBERON:0004252	93.48	gold quality
gastrocnemius	UBERON:0001388	92.78	gold quality
muscle of leg	UBERON:0001383	92.05	gold quality
vastus lateralis	UBERON:0001379	91.74	gold quality
quadriceps femoris	UBERON:0001377	91.69	gold quality
biceps brachii	UBERON:0001507	91.69	gold quality
skeletal muscle tissue	UBERON:0001134	91.26	gold quality
blood	UBERON:0000178	90.55	gold quality
pigmented layer of retina	UBERON:0001782	90.43	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	90.17	gold quality
vermiform appendix	UBERON:0001154	89.90	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	89.10	gold quality
lymph node	UBERON:0000029	88.68	gold quality
deltoid	UBERON:0001476	88.64	gold quality
muscle tissue	UBERON:0002385	88.50	gold quality
tibialis anterior	UBERON:0001385	87.95	gold quality
oviduct epithelium	UBERON:0004804	87.32	gold quality
amniotic fluid	UBERON:0000173	86.70	gold quality
thymus	UBERON:0002370	86.31	gold quality
medial globus pallidus	UBERON:0002477	86.20	gold quality
corpus callosum	UBERON:0002336	84.60	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	84.51	gold quality
putamen	UBERON:0001874	84.03	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.58	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.44	gold quality
caecum	UBERON:0001153	83.26	gold quality
globus pallidus	UBERON:0001875	83.17	gold quality
substantia nigra	UBERON:0002038	82.97	gold quality
amygdala	UBERON:0001876	82.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	18.03

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long noncoding RNA PRKCQ-AS1 promotes CRC cell proliferation and migration via modulating miR-1287-5p/YBX1 axis. (PMID:32619070)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.