PRKG2-AS1

Summary

PRKG2-AS1 (PRKG2 antisense RNA 1, HGNC:40478) is a long non-coding RNA gene on chromosome 4q21.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40478
Approved symbol	PRKG2-AS1
Name	PRKG2 antisense RNA 1
Location	4q21.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251059
Ensembl biotype	lncRNA
Entrez	101928942
RNAcentral	URS00003F5AD3 — lncRNA, 782 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000505175, ENST00000512502, ENST00000663090

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505175 — 5 exons

Exon	Start	End
ENSE00002022620	81175998	81176037
ENSE00002030191	81173875	81173930
ENSE00002050919	81175444	81175591
ENSE00002082590	81193060	81193180
ENSE00002085438	81192180	81192246

Expression profiles

Bgee: expression breadth broad, 61 present calls, max score 89.45.

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.45	gold quality
liver	UBERON:0002107	76.83	silver quality
skeletal muscle tissue	UBERON:0001134	71.57	silver quality
kidney	UBERON:0002113	68.19	silver quality
right testis	UBERON:0004534	67.95	gold quality
left testis	UBERON:0004533	67.12	gold quality
spinal cord	UBERON:0002240	66.74	silver quality
testis	UBERON:0000473	66.42	gold quality
quadriceps femoris	UBERON:0001377	65.49	gold quality
cerebellar vermis	UBERON:0004720	64.61	gold quality
thymus	UBERON:0002370	63.54	silver quality
lymph node	UBERON:0000029	61.81	gold quality
duodenum	UBERON:0002114	59.25	gold quality
multicellular organism	UBERON:0000468	52.89	gold quality
blood	UBERON:0000178	52.79	gold quality
islet of Langerhans	UBERON:0000006	52.14	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	52.13	silver quality
monocyte	CL:0000576	51.41	gold quality
pancreas	UBERON:0001264	50.92	gold quality
gastrocnemius	UBERON:0001388	50.35	gold quality
calcaneal tendon	UBERON:0003701	50.09	silver quality
subcutaneous adipose tissue	UBERON:0002190	49.43	silver quality
body of pancreas	UBERON:0001150	48.83	gold quality
prefrontal cortex	UBERON:0000451	48.53	gold quality
body of stomach	UBERON:0001161	47.80	gold quality
intestine	UBERON:0000160	47.59	gold quality
stomach	UBERON:0000945	47.25	gold quality
small intestine	UBERON:0002108	47.00	gold quality
heart left ventricle	UBERON:0002084	46.74	gold quality
colon	UBERON:0001155	46.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.