PRNT

Summary

PRNT (prion locus lncRNA, testis expressed, HGNC:18046) is a long non-coding RNA gene on chromosome 20p13.

Predicted to be located in extracellular region.

Source: NCBI Gene 149830 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18046
Approved symbol	PRNT
Name	prion locus lncRNA, testis expressed
Location	20p13
Locus type	RNA, long non-coding
Status	Approved
Aliases	M8
Ensembl gene	ENSG00000180259
Ensembl biotype	lncRNA
Entrez	149830
RNAcentral	URS000075DBAC — lncRNA, 2353 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000326539, ENST00000418528, ENST00000423718, ENST00000662883

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000326539 — 2 exons

Exon	Start	End
ENSE00001269041	4740140	4740668
ENSE00001739562	4731282	4733085

Expression profiles

Bgee: expression breadth broad, 13 present calls, max score 90.61.

Top tissues by expression

184 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	90.61	gold quality
left testis	UBERON:0004533	72.79	gold quality
testis	UBERON:0000473	69.31	gold quality
right testis	UBERON:0004534	66.31	gold quality
ileal mucosa	UBERON:0000331	61.11	silver quality
tibialis anterior	UBERON:0001385	56.99	silver quality
tibial nerve	UBERON:0001323	56.92	gold quality
gastrocnemius	UBERON:0001388	56.62	gold quality
skin of leg	UBERON:0001511	55.32	gold quality
pancreatic ductal cell	CL:0002079	55.25	silver quality
islet of Langerhans	UBERON:0000006	54.79	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
epithelial cell of pancreas	CL:0000083	54.07	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
buccal mucosa cell	CL:0002336	53.60	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
deltoid	UBERON:0001476	52.39	gold quality
cardiac atrium	UBERON:0002081	51.83	gold quality
myocardium	UBERON:0002349	50.25	gold quality
quadriceps femoris	UBERON:0001377	47.31	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality
metanephros	UBERON:0000081	46.07	gold quality
skeletal muscle tissue	UBERON:0001134	45.42	gold quality
vastus lateralis	UBERON:0001379	45.40	gold quality
adult mammalian kidney	UBERON:0000082	44.98	gold quality
anatomical system	UBERON:0000467	44.56	gold quality
material anatomical entity	UBERON:0000465	44.36	gold quality
multicellular organism	UBERON:0000468	44.24	gold quality
heart left ventricle	UBERON:0002084	43.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.79

Regulation

Is transcription factor: no

Upstream regulators (CollecTRI, top): CTCF

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.