PROK2-DT

Summary

PROK2-DT (PROK2 divergent transcript, HGNC:58092) is a long non-coding RNA gene on chromosome 3p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58092
Approved symbol	PROK2-DT
Name	PROK2 divergent transcript
Location	3p13
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00006091
Ensembl gene	ENSG00000287131
Ensembl biotype	lncRNA
Entrez	105377156
RNAcentral	URS00005F9D49 — lncRNA, 675 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000658676, ENST00000725818, ENST00000725819, ENST00000725820, ENST00000725821, ENST00000725822, ENST00000725823

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000658676 — 2 exons

Exon	Start	End
ENSE00004049703	71785636	71786425
ENSE00004049704	71785353	71785523

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 91.54.

Top tissues by expression

53 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.54	gold quality
blood	UBERON:0000178	69.66	gold quality
bone marrow cell	CL:0002092	64.99	silver quality
right testis	UBERON:0004534	62.64	gold quality
left testis	UBERON:0004533	62.56	gold quality
multicellular organism	UBERON:0000468	62.11	gold quality
testis	UBERON:0000473	61.97	gold quality
bone marrow	UBERON:0002371	59.11	silver quality
anterior cingulate cortex	UBERON:0009835	57.85	gold quality
leukocyte	CL:0000738	56.08	gold quality
urinary bladder	UBERON:0001255	54.87	gold quality
skin of abdomen	UBERON:0001416	54.73	gold quality
monocyte	CL:0000576	54.43	gold quality
lymph node	UBERON:0000029	51.77	silver quality
liver	UBERON:0002107	51.63	silver quality
granulocyte	CL:0000094	49.81	silver quality
placenta	UBERON:0001987	49.81	gold quality
spleen	UBERON:0002106	48.66	gold quality
pancreas	UBERON:0001264	48.24	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	47.80	gold quality
vermiform appendix	UBERON:0001154	47.40	silver quality
gastrocnemius	UBERON:0001388	46.02	gold quality
transverse colon	UBERON:0001157	45.82	gold quality
hindlimb stylopod muscle	UBERON:0004252	45.62	silver quality
heart	UBERON:0000948	45.42	gold quality
heart left ventricle	UBERON:0002084	45.26	gold quality
small intestine Peyer’s patch	UBERON:0003454	44.61	gold quality
cortex of kidney	UBERON:0001225	44.40	silver quality
ascending aorta	UBERON:0001496	44.33	gold quality
left uterine tube	UBERON:0001303	44.12	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.