PROSER2-AS1

Summary

PROSER2-AS1 (PROSER2 antisense RNA 1, HGNC:27343) is a long non-coding RNA gene on chromosome 10p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27343
Approved symbol	PROSER2-AS1
Name	PROSER2 antisense RNA 1
Location	10p14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225778
Ensembl biotype	lncRNA
Entrez	219731
RNAcentral	URS000075BA57 — lncRNA, 3163 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000445498, ENST00000453242, ENST00000701703, ENST00000829123, ENST00000829124, ENST00000829125, ENST00000829126, ENST00000829127, ENST00000829128, ENST00000829129, ENST00000829130, ENST00000829131, ENST00000829132, ENST00000829133, ENST00000829134, ENST00000829135

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000445498 — 6 exons

Exon	Start	End
ENSE00001596805	11857265	11857385
ENSE00001632387	11862817	11862930
ENSE00001713446	11869366	11869501
ENSE00001714216	11849608	11851756
ENSE00001776411	11894182	11894700
ENSE00001799818	11887847	11887953

Expression profiles

Bgee: expression breadth ubiquitous, 150 present calls, max score 77.48.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 6.6882 / max 331.8917, expressed in 96 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
108261	6.6882	96

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.48	gold quality
colonic epithelium	UBERON:0000397	71.54	silver quality
right testis	UBERON:0004534	69.31	gold quality
left testis	UBERON:0004533	68.44	gold quality
sperm	CL:0000019	66.89	gold quality
testis	UBERON:0000473	66.88	gold quality
right lobe of thyroid gland	UBERON:0001119	66.85	gold quality
superficial temporal artery	UBERON:0001614	66.52	gold quality
germinal epithelium of ovary	UBERON:0001304	66.06	gold quality
left lobe of thyroid gland	UBERON:0001120	65.52	gold quality
thyroid gland	UBERON:0002046	65.12	gold quality
putamen	UBERON:0001874	63.17	gold quality
right lobe of liver	UBERON:0001114	62.83	gold quality
nucleus accumbens	UBERON:0001882	62.62	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.51	gold quality
ventricular zone	UBERON:0003053	62.43	gold quality
caudate nucleus	UBERON:0001873	62.18	gold quality
mucosa of paranasal sinus	UBERON:0005030	62.15	gold quality
apex of heart	UBERON:0002098	62.08	gold quality
adenohypophysis	UBERON:0002196	60.30	gold quality
ganglionic eminence	UBERON:0004023	59.54	gold quality
hypothalamus	UBERON:0001898	59.31	gold quality
cerebellar hemisphere	UBERON:0002245	58.93	gold quality
right atrium auricular region	UBERON:0006631	58.89	gold quality
cerebellar cortex	UBERON:0002129	58.86	gold quality
muscle of leg	UBERON:0001383	58.60	gold quality
cardiac atrium	UBERON:0002081	58.41	gold quality
pituitary gland	UBERON:0000007	58.15	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.87	gold quality
gastrocnemius	UBERON:0001388	57.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.40

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.