PRPF19-DT

Summary

PRPF19-DT (PRPF19 divergent transcript, HGNC:55484) is a long non-coding RNA gene on chromosome 11q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55484
Approved symbol	PRPF19-DT
Name	PRPF19 divergent transcript
Location	11q12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257052
Ensembl biotype	lncRNA
Entrez	107984333
RNAcentral	URS00026A203E — lncRNA, 1978 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000544421, ENST00000751147, ENST00000751148

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000544421 — 2 exons

Exon	Start	End
ENSE00004096096	60906668	60907282
ENSE00004096098	60909427	60910173

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 81.87.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.43	silver quality
bone marrow cell	CL:0002092	71.72	gold quality
thymus	UBERON:0002370	70.67	silver quality
hindlimb stylopod muscle	UBERON:0004252	65.90	gold quality
skeletal muscle tissue	UBERON:0001134	64.62	gold quality
islet of Langerhans	UBERON:0000006	64.57	gold quality
ventricular zone	UBERON:0003053	63.04	gold quality
colonic epithelium	UBERON:0000397	62.46	silver quality
tonsil	UBERON:0002372	62.45	gold quality
quadriceps femoris	UBERON:0001377	61.63	gold quality
bone marrow	UBERON:0002371	61.07	silver quality
muscle of leg	UBERON:0001383	60.65	gold quality
gastrocnemius	UBERON:0001388	60.30	gold quality
blood	UBERON:0000178	60.28	gold quality
liver	UBERON:0002107	59.95	gold quality
ganglionic eminence	UBERON:0004023	59.91	gold quality
pancreas	UBERON:0001264	59.79	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.59	gold quality
fallopian tube	UBERON:0003889	58.51	gold quality
cerebellar vermis	UBERON:0004720	58.50	gold quality
monocyte	CL:0000576	57.63	gold quality
leukocyte	CL:0000738	57.46	gold quality
left adrenal gland	UBERON:0001234	57.29	gold quality
right lobe of liver	UBERON:0001114	57.16	gold quality
body of pancreas	UBERON:0001150	56.91	gold quality
right uterine tube	UBERON:0001302	56.85	gold quality
adrenal gland	UBERON:0002369	56.61	gold quality
duodenum	UBERON:0002114	56.51	gold quality
prefrontal cortex	UBERON:0000451	56.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.