PRPF39-DT

Summary

PRPF39-DT (PRPF39 divergent transcript, HGNC:55576) is a long non-coding RNA gene on chromosome 14q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55576
Approved symbol	PRPF39-DT
Name	PRPF39 divergent transcript
Location	14q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249163
Ensembl biotype	lncRNA
Entrez	105370474
RNAcentral	URS00026A23FE — lncRNA, 895 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000556389, ENST00000730532, ENST00000730533

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000556389 — 2 exons

Exon	Start	End
ENSE00002070776	45083472	45083977
ENSE00002456195	45083045	45083387

Expression profiles

Bgee: expression breadth broad, 42 present calls, max score 86.53.

Top tissues by expression

169 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	86.53	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.40	gold quality
kidney epithelium	UBERON:0004819	83.18	gold quality
parotid gland	UBERON:0001831	81.99	gold quality
sperm	CL:0000019	80.67	gold quality
nasal cavity epithelium	UBERON:0005384	74.86	gold quality
left testis	UBERON:0004533	74.43	gold quality
right testis	UBERON:0004534	73.95	gold quality
myocardium	UBERON:0002349	73.70	gold quality
left ventricle myocardium	UBERON:0006566	73.34	gold quality
cardiac muscle of right atrium	UBERON:0003379	72.77	gold quality
testis	UBERON:0000473	72.62	gold quality
pancreatic ductal cell	CL:0002079	72.51	silver quality
heart right ventricle	UBERON:0002080	71.15	gold quality
upper arm skin	UBERON:0004263	70.70	gold quality
vastus lateralis	UBERON:0001379	70.31	gold quality
vena cava	UBERON:0004087	70.30	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	70.20	gold quality
quadriceps femoris	UBERON:0001377	69.66	gold quality
postcentral gyrus	UBERON:0002581	69.13	gold quality
cerebellar vermis	UBERON:0004720	68.88	gold quality
skeletal muscle tissue	UBERON:0001134	68.49	gold quality
parietal lobe	UBERON:0001872	68.38	gold quality
superior frontal gyrus	UBERON:0002661	68.38	gold quality
cerebellar hemisphere	UBERON:0002245	68.25	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	67.21	gold quality
entorhinal cortex	UBERON:0002728	67.07	gold quality
biceps brachii	UBERON:0001507	67.06	gold quality
oocyte	CL:0000023	66.95	gold quality
secondary oocyte	CL:0000655	66.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.66

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.