PRRX2-AS1

Summary

PRRX2-AS1 (PRRX2 antisense RNA 1, HGNC:50684) is a long non-coding RNA gene on chromosome 9q34.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50684
Approved symbol	PRRX2-AS1
Name	PRRX2 antisense RNA 1
Location	9q34.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236024
Ensembl biotype	lncRNA
Entrez	101929437
RNAcentral	URS00008E39F9 — lncRNA, 502 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000440413, ENST00000737889

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440413 — 2 exons

Exon	Start	End
ENSE00004072637	129712891	129713261
ENSE00004072638	129718573	129718747

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 88.68.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0107 / max 11.2771, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
102752	0.0107	3

Top tissues by expression

210 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	88.68	gold quality
left testis	UBERON:0004533	88.58	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.05	gold quality
sperm	CL:0000019	86.89	gold quality
testis	UBERON:0000473	85.86	gold quality
pancreatic ductal cell	CL:0002079	85.84	silver quality
epithelial cell of pancreas	CL:0000083	84.34	gold quality
tibialis anterior	UBERON:0001385	82.05	silver quality
upper arm skin	UBERON:0004263	81.49	gold quality
buccal mucosa cell	CL:0002336	80.36	gold quality
ileal mucosa	UBERON:0000331	73.93	gold quality
deltoid	UBERON:0001476	73.77	gold quality
adult organism	UBERON:0007023	73.39	gold quality
endothelial cell	CL:0000115	72.34	gold quality
bone marrow	UBERON:0002371	71.68	gold quality
kidney epithelium	UBERON:0004819	71.35	gold quality
cardiac muscle of right atrium	UBERON:0003379	70.75	gold quality
left ventricle myocardium	UBERON:0006566	70.34	gold quality
vena cava	UBERON:0004087	69.35	gold quality
amniotic fluid	UBERON:0000173	68.44	gold quality
islet of Langerhans	UBERON:0000006	67.80	gold quality
skeletal muscle tissue	UBERON:0001134	67.35	gold quality
nasal cavity epithelium	UBERON:0005384	67.32	gold quality
layer of synovial tissue	UBERON:0007616	67.30	gold quality
cerebellar vermis	UBERON:0004720	67.22	silver quality
myocardium	UBERON:0002349	66.69	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	66.46	gold quality
oocyte	CL:0000023	66.40	gold quality
pharyngeal mucosa	UBERON:0000355	66.38	gold quality
gingival epithelium	UBERON:0001949	65.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.