PSLNR

Summary

PSLNR (prostate enriched lncRNA, HGNC:54405) is a long non-coding RNA gene on chromosome 22q11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54405
Approved symbol	PSLNR
Name	prostate enriched lncRNA
Location	22q11.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	LA16c-83F12.6
Ensembl gene	ENSG00000225255
Ensembl biotype	lncRNA
Entrez	106146148
RNAcentral	URS000194B0E6 — lncRNA, 1157 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000438574, ENST00000453395, ENST00000806611, ENST00000809119, ENST00000809120, ENST00000809121, ENST00000809122, ENST00000809123, ENST00000809124, ENST00000809125, ENST00000809126, ENST00000809127, ENST00000809128, ENST00000809129

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438574 — 3 exons

Exon	Start	End
ENSE00001617515	15765687	15765780
ENSE00001715873	15778010	15778297
ENSE00001784645	15774712	15774848

Expression profiles

Bgee: expression breadth broad, 91 present calls, max score 86.81.

Top tissues by expression

91 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
prostate gland	UBERON:0002367	86.81	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.89	gold quality
right testis	UBERON:0004534	83.99	gold quality
left testis	UBERON:0004533	83.71	gold quality
testis	UBERON:0000473	82.75	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.66	gold quality
bone marrow cell	CL:0002092	68.58	silver quality
stromal cell of endometrium	CL:0002255	61.00	gold quality
left uterine tube	UBERON:0001303	60.76	gold quality
monocyte	CL:0000576	55.80	gold quality
multicellular organism	UBERON:0000468	55.54	gold quality
placenta	UBERON:0001987	53.44	gold quality
prefrontal cortex	UBERON:0000451	53.27	gold quality
lymph node	UBERON:0000029	53.20	gold quality
tonsil	UBERON:0002372	52.14	silver quality
endometrium	UBERON:0001295	52.09	gold quality
blood	UBERON:0000178	50.14	gold quality
thoracic mammary gland	UBERON:0005200	49.64	gold quality
fallopian tube	UBERON:0003889	48.86	gold quality
muscle of leg	UBERON:0001383	48.47	gold quality
cortex of kidney	UBERON:0001225	48.42	silver quality
gastrocnemius	UBERON:0001388	47.67	gold quality
right coronary artery	UBERON:0001625	47.00	gold quality
body of pancreas	UBERON:0001150	45.94	gold quality
endocervix	UBERON:0000458	45.83	gold quality
primary visual cortex	UBERON:0002436	45.59	silver quality
left lobe of thyroid gland	UBERON:0001120	45.40	gold quality
heart left ventricle	UBERON:0002084	45.17	gold quality
cerebellar cortex	UBERON:0002129	44.92	silver quality
left adrenal gland	UBERON:0001234	44.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.28

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Our study revealed for the first time a novel androgen-reduced prostate-specific lncRNA, PSLNR, which inhibited prostate cancer progression via the p53-dependent pathway. (PMID:31269242)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.