PSMD6-AS1

Summary

PSMD6-AS1 (PSMD6 antisense RNA 1, HGNC:40480) is a long non-coding RNA gene on chromosome 3p14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40480
Approved symbol	PSMD6-AS1
Name	PSMD6 antisense RNA 1
Location	3p14.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000462717, lnc00462717
Ensembl gene	ENSG00000243410
Ensembl biotype	lncRNA
Entrez	109729140
RNAcentral	URS0002853A7A — lncRNA, 457 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000462717

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000462717 — 2 exons

Exon	Start	End
ENSE00001872357	64011964	64012042
ENSE00001895092	64015885	64016246

Expression profiles

Bgee: expression breadth broad, 85 present calls, max score 83.06.

Top tissues by expression

85 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.06	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.63	silver quality
skeletal muscle tissue	UBERON:0001134	75.84	silver quality
bone marrow cell	CL:0002092	73.05	gold quality
ganglionic eminence	UBERON:0004023	67.76	gold quality
liver	UBERON:0002107	65.23	gold quality
ventricular zone	UBERON:0003053	63.79	gold quality
blood	UBERON:0000178	61.07	gold quality
leukocyte	CL:0000738	60.18	gold quality
monocyte	CL:0000576	59.95	gold quality
cortical plate	UBERON:0005343	58.87	silver quality
urinary bladder	UBERON:0001255	58.75	gold quality
right lobe of liver	UBERON:0001114	56.96	gold quality
kidney	UBERON:0002113	56.64	gold quality
prefrontal cortex	UBERON:0000451	56.16	gold quality
thoracic mammary gland	UBERON:0005200	56.09	gold quality
myometrium	UBERON:0001296	55.70	gold quality
muscle of leg	UBERON:0001383	55.48	gold quality
primary visual cortex	UBERON:0002436	55.21	gold quality
gastrocnemius	UBERON:0001388	55.08	gold quality
heart left ventricle	UBERON:0002084	52.90	gold quality
adult mammalian kidney	UBERON:0000082	52.52	gold quality
stomach	UBERON:0000945	51.93	gold quality
left coronary artery	UBERON:0001626	51.92	gold quality
heart	UBERON:0000948	51.80	gold quality
islet of Langerhans	UBERON:0000006	51.03	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.95	gold quality
Brodmann (1909) area 9	UBERON:0013540	50.55	gold quality
body of pancreas	UBERON:0001150	50.38	gold quality
tibial artery	UBERON:0007610	50.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Data show that long noncoding RNAs lnc00462717 direct target MDM2 protein and regulate MAPK relevant pathway expression. (PMID:28189682)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.