PTCHD1-AS

Summary

PTCHD1-AS (PTCHD1 and PHEX antisense RNA, HGNC:37703) is a long non-coding RNA gene on chromosome Xp22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37703
Approved symbol	PTCHD1-AS
Name	PTCHD1 and PHEX antisense RNA
Location	Xp22.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	PTCHD1AS1, PTCHD1AS2, DDX53-AS1
Ensembl gene	ENSG00000233067
Ensembl biotype	lncRNA
OMIM	301140
Entrez	100873065
RNAcentral	URS0000A76DB3 — lncRNA, 3772 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000424650, ENST00000669979, ENST00000687119, ENST00000687248, ENST00000715857, ENST00000796453, ENST00000799269, ENST00000799270, ENST00000819916, ENST00000825156, ENST00000825157, ENST00000825158, ENST00000825159

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424650 — 5 exons

Exon	Start	End
ENSE00001658112	22169794	22169855
ENSE00001671565	22171510	22171644
ENSE00001701462	22171159	22171190
ENSE00001734605	22162733	22163371
ENSE00001801931	22171946	22172983

Expression profiles

Bgee: expression breadth broad, 75 present calls, max score 69.44.

Top tissues by expression

75 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	69.44	silver quality
ganglionic eminence	UBERON:0004023	59.09	gold quality
pancreas	UBERON:0001264	54.27	gold quality
prefrontal cortex	UBERON:0000451	53.65	gold quality
skeletal muscle tissue	UBERON:0001134	51.87	silver quality
islet of Langerhans	UBERON:0000006	51.22	gold quality
skin of leg	UBERON:0001511	51.05	gold quality
cerebellum	UBERON:0002037	49.09	silver quality
monocyte	CL:0000576	49.08	silver quality
cerebellar cortex	UBERON:0002129	48.99	silver quality
cerebellar hemisphere	UBERON:0002245	48.83	silver quality
ovary	UBERON:0000992	48.58	silver quality
frontal cortex	UBERON:0001870	48.52	gold quality
right hemisphere of cerebellum	UBERON:0014890	47.49	silver quality
lymph node	UBERON:0000029	47.18	silver quality
muscle of leg	UBERON:0001383	47.02	silver quality
myometrium	UBERON:0001296	46.78	gold quality
duodenum	UBERON:0002114	46.74	silver quality
placenta	UBERON:0001987	45.92	silver quality
lung	UBERON:0002048	45.57	silver quality
blood	UBERON:0000178	45.54	silver quality
superior frontal gyrus	UBERON:0002661	45.54	silver quality
cerebral cortex	UBERON:0000956	45.01	gold quality
urinary bladder	UBERON:0001255	44.92	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	44.74	silver quality
vagina	UBERON:0000996	44.40	gold quality
gastrocnemius	UBERON:0001388	44.30	silver quality
stomach	UBERON:0000945	44.26	silver quality
brain	UBERON:0000955	44.19	gold quality
right lobe of thyroid gland	UBERON:0001119	43.90	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.