PTOV1-AS1

Summary

PTOV1-AS1 (PTOV1 antisense RNA 1, HGNC:44174) is a long non-coding RNA gene on chromosome 19q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44174
Approved symbol	PTOV1-AS1
Name	PTOV1 antisense RNA 1
Location	19q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000268006
Ensembl biotype	lncRNA
Entrez	100506033
RNAcentral	URS000075E054 — lncRNA, 2161 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000596521, ENST00000600742, ENST00000835604

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000596521 — 4 exons

Exon	Start	End
ENSE00002989961	49851568	49851676
ENSE00003023479	49844316	49844892
ENSE00003027632	49838639	49840076
ENSE00003030750	49846723	49846753

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 82.33.

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.33	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.03	gold quality
islet of Langerhans	UBERON:0000006	70.54	gold quality
bone marrow cell	CL:0002092	69.11	silver quality
gastrocnemius	UBERON:0001388	67.82	gold quality
pancreatic ductal cell	CL:0002079	67.63	silver quality
muscle of leg	UBERON:0001383	67.45	gold quality
sperm	CL:0000019	67.20	silver quality
adrenal tissue	UBERON:0018303	66.70	gold quality
right lobe of thyroid gland	UBERON:0001119	66.47	gold quality
left ovary	UBERON:0002119	66.40	gold quality
left lobe of thyroid gland	UBERON:0001120	66.07	gold quality
right uterine tube	UBERON:0001302	65.90	gold quality
ventricular zone	UBERON:0003053	65.84	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.75	gold quality
thyroid gland	UBERON:0002046	65.53	gold quality
adenohypophysis	UBERON:0002196	65.47	gold quality
right adrenal gland	UBERON:0001233	65.46	gold quality
left adrenal gland	UBERON:0001234	65.23	gold quality
left adrenal gland cortex	UBERON:0035825	65.23	gold quality
stromal cell of endometrium	CL:0002255	65.04	gold quality
right adrenal gland cortex	UBERON:0035827	65.03	gold quality
pituitary gland	UBERON:0000007	64.83	gold quality
right ovary	UBERON:0002118	64.22	gold quality
pancreas	UBERON:0001264	64.04	gold quality
vena cava	UBERON:0004087	63.84	gold quality
corpus epididymis	UBERON:0004359	63.75	silver quality
adrenal cortex	UBERON:0001235	63.72	gold quality
adrenal gland	UBERON:0002369	63.63	gold quality
ganglionic eminence	UBERON:0004023	63.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.53

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Upregulation of lncRNA PTOV1-AS1 in hepatocellular carcinoma contributes to disease progression and sorafenib resistance through regulating miR-505. (PMID:37352125)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.