PTPN23-DT

Summary

PTPN23-DT (PTPN23 divergent transcript, HGNC:55397) is a long non-coding RNA gene on chromosome 3p21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55397
Approved symbol	PTPN23-DT
Name	PTPN23 divergent transcript
Location	3p21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260236
Ensembl biotype	lncRNA
Entrez	119863865
RNAcentral	URS0002339EE8 — lncRNA, 2401 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000568593

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000568593 — 1 exons

Exon	Start	End
ENSE00004172942	47379079	47381620

Expression profiles

Bgee: expression breadth ubiquitous, 202 present calls, max score 83.39.

Top tissues by expression

234 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	83.39	gold quality
sural nerve	UBERON:0015488	73.12	gold quality
tendon of biceps brachii	UBERON:0008188	68.05	gold quality
stromal cell of endometrium	CL:0002255	66.52	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.21	gold quality
medial globus pallidus	UBERON:0002477	65.99	gold quality
tendon	UBERON:0000043	65.83	gold quality
spinal cord	UBERON:0002240	65.77	gold quality
bone marrow cell	CL:0002092	65.72	silver quality
ventricular zone	UBERON:0003053	65.56	gold quality
pituitary gland	UBERON:0000007	65.34	gold quality
amygdala	UBERON:0001876	65.08	gold quality
globus pallidus	UBERON:0001875	65.06	gold quality
cerebellar vermis	UBERON:0004720	64.94	gold quality
right coronary artery	UBERON:0001625	64.79	gold quality
substantia nigra	UBERON:0002038	64.71	gold quality
body of uterus	UBERON:0009853	64.47	gold quality
granulocyte	CL:0000094	64.39	gold quality
midbrain	UBERON:0001891	64.35	gold quality
adenohypophysis	UBERON:0002196	64.34	gold quality
cerebellar cortex	UBERON:0002129	64.13	gold quality
cerebellum	UBERON:0002037	64.08	gold quality
mucosa of transverse colon	UBERON:0004991	64.08	gold quality
cerebellar hemisphere	UBERON:0002245	64.02	gold quality
right uterine tube	UBERON:0001302	63.78	gold quality
colonic epithelium	UBERON:0000397	63.75	silver quality
hypothalamus	UBERON:0001898	63.66	gold quality
right lobe of thyroid gland	UBERON:0001119	63.55	gold quality
prefrontal cortex	UBERON:0000451	63.52	gold quality
anterior cingulate cortex	UBERON:0009835	63.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.