PTPRB-AS1

Summary

PTPRB-AS1 (PTPRB antisense RNA 1, HGNC:58150) is a long non-coding RNA gene on chromosome 12q15.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58150
Approved symbol	PTPRB-AS1
Name	PTPRB antisense RNA 1
Location	12q15
Locus type	RNA, long non-coding
Status	Approved
Aliases	SNX20AR
Ensembl gene	ENSG00000258168
Ensembl biotype	lncRNA
Entrez	105369828
RNAcentral	URS0000761F49 — lncRNA, 5903 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000546836, ENST00000547656, ENST00000548687, ENST00000548924, ENST00000549359, ENST00000549460, ENST00000549616, ENST00000551438, ENST00000667308, ENST00000667427, ENST00000723544

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546836 — 3 exons

Exon	Start	End
ENSE00002372728	70520206	70520267
ENSE00002388821	70538050	70538663
ENSE00002394612	70522524	70522630

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 79.58.

Top tissues by expression

253 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.58	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.36	gold quality
colonic epithelium	UBERON:0000397	75.65	gold quality
bone marrow cell	CL:0002092	74.22	gold quality
right lung	UBERON:0002167	74.21	gold quality
sural nerve	UBERON:0015488	74.14	gold quality
upper lobe of left lung	UBERON:0008952	72.49	gold quality
calcaneal tendon	UBERON:0003701	70.89	gold quality
apex of heart	UBERON:0002098	70.64	gold quality
upper lobe of lung	UBERON:0008948	70.35	gold quality
gastrocnemius	UBERON:0001388	69.07	gold quality
subcutaneous adipose tissue	UBERON:0002190	69.04	gold quality
tonsil	UBERON:0002372	68.89	gold quality
muscle of leg	UBERON:0001383	68.59	gold quality
tibialis anterior	UBERON:0001385	68.54	silver quality
vermiform appendix	UBERON:0001154	67.75	gold quality
secondary oocyte	CL:0000655	67.50	gold quality
spleen	UBERON:0002106	67.46	gold quality
omental fat pad	UBERON:0010414	67.22	gold quality
peritoneum	UBERON:0002358	67.20	gold quality
caecum	UBERON:0001153	66.55	gold quality
metanephros cortex	UBERON:0010533	66.54	gold quality
upper arm skin	UBERON:0004263	66.50	gold quality
tibial nerve	UBERON:0001323	66.49	gold quality
ventricular zone	UBERON:0003053	66.32	gold quality
mucosa of stomach	UBERON:0001199	66.10	gold quality
ileal mucosa	UBERON:0000331	65.83	silver quality
right atrium auricular region	UBERON:0006631	65.78	gold quality
adipose tissue of abdominal region	UBERON:0007808	65.76	gold quality
corpus callosum	UBERON:0002336	65.36	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	7.79
E-ANND-3	yes	5.19

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.