PTPRD-AS1

Summary

PTPRD-AS1 (PTPRD antisense RNA 1, HGNC:49753) is a long non-coding RNA gene on chromosome 9p24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49753
Approved symbol	PTPRD-AS1
Name	PTPRD antisense RNA 1
Location	9p24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225706
Ensembl biotype	lncRNA
Entrez	101929407
RNAcentral	URS000075D31A — lncRNA, 1334 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000430766, ENST00000447950, ENST00000665783, ENST00000666050, ENST00000846146

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430766 — 2 exons

Exon	Start	End
ENSE00004273667	8859956	8861724
ENSE00004273668	8857985	8858323

Expression profiles

Bgee: expression breadth ubiquitous, 163 present calls, max score 86.07.

FANTOM5 (CAGE): breadth broad, TPM avg 1.8557 / max 84.0440, expressed in 501 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
96025	1.3902	452
96023	0.2346	104
96026	0.1369	81
96024	0.0940	53

Top tissues by expression

229 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	86.07	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	83.09	gold quality
ganglionic eminence	UBERON:0004023	79.58	gold quality
spinal cord	UBERON:0002240	79.51	gold quality
right coronary artery	UBERON:0001625	77.96	gold quality
left ovary	UBERON:0002119	77.52	gold quality
cerebellar hemisphere	UBERON:0002245	76.69	gold quality
cerebellar cortex	UBERON:0002129	76.67	gold quality
right ovary	UBERON:0002118	76.64	gold quality
secondary oocyte	CL:0000655	76.55	silver quality
right hemisphere of cerebellum	UBERON:0014890	76.38	gold quality
caudate nucleus	UBERON:0001873	76.18	gold quality
putamen	UBERON:0001874	75.91	gold quality
Brodmann (1909) area 9	UBERON:0013540	75.20	gold quality
cerebellum	UBERON:0002037	74.88	gold quality
prefrontal cortex	UBERON:0000451	74.36	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.31	gold quality
ovary	UBERON:0000992	74.11	gold quality
anterior cingulate cortex	UBERON:0009835	73.74	gold quality
hypothalamus	UBERON:0001898	73.39	gold quality
nucleus accumbens	UBERON:0001882	73.37	gold quality
right frontal lobe	UBERON:0002810	72.82	gold quality
left coronary artery	UBERON:0001626	72.57	gold quality
amygdala	UBERON:0001876	72.05	gold quality
descending thoracic aorta	UBERON:0002345	71.95	gold quality
ventricular zone	UBERON:0003053	71.87	gold quality
substantia nigra	UBERON:0002038	71.32	gold quality
coronary artery	UBERON:0001621	71.25	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	71.25	gold quality
thoracic aorta	UBERON:0001515	70.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.91

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.