PTPRD-DT

Summary

PTPRD-DT (PTPRD divergent transcript, HGNC:49754) is a long non-coding RNA gene on chromosome 9p23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49754
Approved symbol	PTPRD-DT
Name	PTPRD divergent transcript
Location	9p23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226717
Ensembl biotype	lncRNA
Entrez	101929428
RNAcentral	URS000075AF9F — lncRNA, 2834 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000429581, ENST00000722270, ENST00000722271, ENST00000722272, ENST00000722273, ENST00000722274

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429581 — 3 exons

Exon	Start	End
ENSE00001672730	10613202	10613426
ENSE00001677837	10617861	10620420
ENSE00001749849	10616617	10616669

Expression profiles

Bgee: expression breadth broad, 29 present calls, max score 71.98.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1017 / max 14.3536, expressed in 56 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
96033	0.1017	56

Top tissues by expression

29 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	71.98	silver quality
cortical plate	UBERON:0005343	60.09	gold quality
prefrontal cortex	UBERON:0000451	54.63	gold quality
superior frontal gyrus	UBERON:0002661	52.06	gold quality
frontal cortex	UBERON:0001870	51.20	gold quality
cerebral cortex	UBERON:0000956	48.49	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	47.00	gold quality
primary visual cortex	UBERON:0002436	46.97	silver quality
Brodmann (1909) area 9	UBERON:0013540	46.72	gold quality
brain	UBERON:0000955	45.75	gold quality
right frontal lobe	UBERON:0002810	45.72	gold quality
islet of Langerhans	UBERON:0000006	45.55	silver quality
anterior cingulate cortex	UBERON:0009835	45.52	gold quality
gastrocnemius	UBERON:0001388	45.05	silver quality
body of pancreas	UBERON:0001150	43.53	silver quality
right hemisphere of cerebellum	UBERON:0014890	43.40	gold quality
Ammon’s horn	UBERON:0001954	42.39	silver quality
cerebellar hemisphere	UBERON:0002245	42.13	gold quality
temporal lobe	UBERON:0001871	41.50	silver quality
amygdala	UBERON:0001876	40.85	silver quality
hypothalamus	UBERON:0001898	40.44	gold quality
substantia nigra	UBERON:0002038	40.30	gold quality
nucleus accumbens	UBERON:0001882	39.78	silver quality
putamen	UBERON:0001874	39.71	silver quality
tibial artery	UBERON:0007610	39.67	silver quality
caudate nucleus	UBERON:0001873	39.65	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	39.18	silver quality
pituitary gland	UBERON:0000007	38.20	silver quality
adenohypophysis	UBERON:0002196	33.23	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.