PTPRK-AS1

Summary

PTPRK-AS1 (PTPRK antisense RNA 1, HGNC:40484) is a long non-coding RNA gene on chromosome 6q22.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40484
Approved symbol	PTPRK-AS1
Name	PTPRK antisense RNA 1
Location	6q22.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227945
Ensembl biotype	lncRNA
Entrez	101928140
RNAcentral	URS00007E41C2 — lncRNA, 1828 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000417390

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417390 — 5 exons

Exon	Start	End
ENSE00001644220	128083671	128083809
ENSE00001657071	128062702	128062821
ENSE00001783351	128027886	128027923
ENSE00001793299	128084904	128085248
ENSE00001796379	128067487	128067596

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 80.16.

Top tissues by expression

225 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.16	gold quality
colonic epithelium	UBERON:0000397	72.25	gold quality
bone marrow cell	CL:0002092	69.02	silver quality
ventricular zone	UBERON:0003053	68.98	gold quality
cortical plate	UBERON:0005343	67.67	gold quality
calcaneal tendon	UBERON:0003701	63.45	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.38	gold quality
corpus callosum	UBERON:0002336	61.33	gold quality
endocervix	UBERON:0000458	60.03	gold quality
monocyte	CL:0000576	58.90	gold quality
tendon	UBERON:0000043	54.65	gold quality
ectocervix	UBERON:0012249	54.11	gold quality
lymph node	UBERON:0000029	53.46	gold quality
right lobe of liver	UBERON:0001114	52.83	gold quality
vermiform appendix	UBERON:0001154	51.79	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.29	gold quality
adrenal tissue	UBERON:0018303	51.27	gold quality
uterine cervix	UBERON:0000002	50.69	gold quality
upper lobe of left lung	UBERON:0008952	50.47	gold quality
right atrium auricular region	UBERON:0006631	50.45	gold quality
body of uterus	UBERON:0009853	50.41	gold quality
prefrontal cortex	UBERON:0000451	50.31	gold quality
cardiac atrium	UBERON:0002081	49.99	gold quality
islet of Langerhans	UBERON:0000006	49.87	gold quality
gall bladder	UBERON:0002110	49.77	gold quality
omental fat pad	UBERON:0010414	49.46	gold quality
peritoneum	UBERON:0002358	49.41	gold quality
stomach	UBERON:0000945	48.97	gold quality
muscle of leg	UBERON:0001383	48.94	gold quality
vagina	UBERON:0000996	48.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.