PTPRN2-AS1

Summary

PTPRN2-AS1 (PTPRN2 antisense RNA 1, HGNC:40488) is a long non-coding RNA gene on chromosome 7q36.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40488
Approved symbol	PTPRN2-AS1
Name	PTPRN2 antisense RNA 1
Location	7q36.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233038
Ensembl biotype	lncRNA
Entrez	100506585
RNAcentral	URS000075C020 — lncRNA, 4319 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000434059, ENST00000436151, ENST00000443338, ENST00000703025

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434059 — 2 exons

Exon	Start	End
ENSE00003987618	157854608	157854875
ENSE00003987619	157857290	157857685

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 86.93.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8728 / max 50.6099, expressed in 221 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
82300	0.3854	155
82302	0.3534	147
82301	0.0924	38
82298	0.0231	7
82299	0.0184	6

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	86.93	gold quality
leukocyte	CL:0000738	86.44	gold quality
granulocyte	CL:0000094	81.51	gold quality
blood	UBERON:0000178	75.01	gold quality
vermiform appendix	UBERON:0001154	74.98	gold quality
bone marrow cell	CL:0002092	74.04	gold quality
bone marrow	UBERON:0002371	73.12	gold quality
colonic epithelium	UBERON:0000397	69.35	silver quality
spleen	UBERON:0002106	67.77	gold quality
duodenum	UBERON:0002114	66.88	gold quality
gall bladder	UBERON:0002110	65.78	gold quality
cortical plate	UBERON:0005343	65.59	gold quality
lymph node	UBERON:0000029	65.56	gold quality
ganglionic eminence	UBERON:0004023	64.85	gold quality
placenta	UBERON:0001987	63.63	gold quality
smooth muscle tissue	UBERON:0001135	62.10	gold quality
lung	UBERON:0002048	61.52	gold quality
right lobe of liver	UBERON:0001114	61.11	gold quality
liver	UBERON:0002107	60.90	gold quality
upper lobe of left lung	UBERON:0008952	60.48	gold quality
sural nerve	UBERON:0015488	59.89	silver quality
skeletal muscle tissue	UBERON:0001134	58.74	gold quality
rectum	UBERON:0001052	58.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.91	gold quality
right lung	UBERON:0002167	57.73	gold quality
islet of Langerhans	UBERON:0000006	57.40	gold quality
small intestine	UBERON:0002108	57.00	gold quality
right coronary artery	UBERON:0001625	56.97	gold quality
urinary bladder	UBERON:0001255	55.84	gold quality
right adrenal gland	UBERON:0001233	55.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.99

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.