PTPRT-AS1

Summary

PTPRT-AS1 (PTPRT antisense RNA 1, HGNC:40491) is a long non-coding RNA gene on chromosome 20q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40491
Approved symbol	PTPRT-AS1
Name	PTPRT antisense RNA 1
Location	20q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227599
Ensembl biotype	lncRNA
Entrez	101927138
RNAcentral	URS0000BC45EC — lncRNA, 1600 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000412519

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412519 — 2 exons

Exon	Start	End
ENSE00001738109	42970826	42971492
ENSE00001781139	42968743	42969661

Expression profiles

Bgee: expression breadth broad, 11 present calls, max score 88.52.

Top tissues by expression

170 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.52	gold quality
sperm	CL:0000019	69.55	gold quality
buccal mucosa cell	CL:0002336	51.94	gold quality
upper lobe of lung	UBERON:0008948	50.02	silver quality
lower lobe of lung	UBERON:0008949	49.93	silver quality
gastrocnemius	UBERON:0001388	49.21	gold quality
left testis	UBERON:0004533	48.76	gold quality
right testis	UBERON:0004534	48.55	gold quality
testis	UBERON:0000473	47.91	gold quality
islet of Langerhans	UBERON:0000006	47.82	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
lung	UBERON:0002048	43.17	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
blood	UBERON:0000178	42.04	gold quality
heart left ventricle	UBERON:0002084	41.97	gold quality
vastus lateralis	UBERON:0001379	41.68	gold quality
quadriceps femoris	UBERON:0001377	41.63	gold quality
prefrontal cortex	UBERON:0000451	41.35	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
middle temporal gyrus	UBERON:0002771	41.29	gold quality
material anatomical entity	UBERON:0000465	41.28	silver quality
anatomical system	UBERON:0000467	41.25	silver quality
multicellular organism	UBERON:0000468	41.20	silver quality
cardiac ventricle	UBERON:0002082	41.15	gold quality
bone marrow	UBERON:0002371	41.14	gold quality
skeletal muscle tissue	UBERON:0001134	41.10	gold quality
palpebral conjunctiva	UBERON:0001812	41.10	gold quality
mucosa of paranasal sinus	UBERON:0005030	40.98	gold quality
heart	UBERON:0000948	40.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.