PTPRT-DT

Summary

PTPRT-DT (PTPRT divergent transcript, HGNC:55715) is a long non-coding RNA gene on chromosome 20q13.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55715
Approved symbol	PTPRT-DT
Name	PTPRT divergent transcript
Location	20q13.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc-SRSF6-1
Ensembl gene	ENSG00000233508
Ensembl biotype	lncRNA
Entrez	121853075
RNAcentral	URS00026A1D9B — lncRNA, 2190 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000430025, ENST00000611791, ENST00000658035, ENST00000670415, ENST00000846263, ENST00000846264, ENST00000846265, ENST00000846266

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430025 — 2 exons

Exon	Start	End
ENSE00001602864	43200596	43201371
ENSE00001621662	43190222	43190250

Expression profiles

Bgee: expression breadth broad, 76 present calls, max score 80.31.

Top tissues by expression

76 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
superior frontal gyrus	UBERON:0002661	80.31	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.87	gold quality
Brodmann (1909) area 9	UBERON:0013540	77.47	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	77.41	gold quality
prefrontal cortex	UBERON:0000451	77.00	gold quality
frontal cortex	UBERON:0001870	76.30	gold quality
anterior cingulate cortex	UBERON:0009835	75.65	gold quality
right frontal lobe	UBERON:0002810	74.54	gold quality
cerebral cortex	UBERON:0000956	73.84	gold quality
primary visual cortex	UBERON:0002436	73.11	gold quality
cortical plate	UBERON:0005343	72.57	gold quality
nucleus accumbens	UBERON:0001882	71.78	gold quality
putamen	UBERON:0001874	70.35	gold quality
caudate nucleus	UBERON:0001873	69.63	gold quality
brain	UBERON:0000955	68.20	gold quality
temporal lobe	UBERON:0001871	67.00	gold quality
amygdala	UBERON:0001876	66.90	gold quality
hypothalamus	UBERON:0001898	64.42	gold quality
colonic epithelium	UBERON:0000397	62.87	silver quality
ganglionic eminence	UBERON:0004023	62.00	gold quality
multicellular organism	UBERON:0000468	61.93	gold quality
adrenal gland	UBERON:0002369	61.68	gold quality
ventricular zone	UBERON:0003053	61.49	gold quality
islet of Langerhans	UBERON:0000006	60.55	gold quality
pancreas	UBERON:0001264	58.60	gold quality
Ammon’s horn	UBERON:0001954	58.29	gold quality
adenohypophysis	UBERON:0002196	58.10	gold quality
pituitary gland	UBERON:0000007	55.05	gold quality
liver	UBERON:0002107	52.44	silver quality
corpus callosum	UBERON:0002336	52.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.