PUS1-AS1

Summary

PUS1-AS1 (PUS1 antisense RNA 1, HGNC:40706) is a long non-coding RNA gene on chromosome 12q24.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40706
Approved symbol	PUS1-AS1
Name	PUS1 antisense RNA 1
Location	12q24.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC131009.1
Ensembl gene	ENSG00000255992
Ensembl biotype	lncRNA
Entrez	107984455
RNAcentral	URS0002A3D54E — lncRNA, 1177 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000539078, ENST00000828047, ENST00000828048, ENST00000828049

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000539078 — 3 exons

Exon	Start	End
ENSE00002302031	131927963	131928190
ENSE00004240462	131924280	131924766
ENSE00004240465	131929185	131929646

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 95.65.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	95.65	gold quality
cortical plate	UBERON:0005343	71.66	gold quality
apex of heart	UBERON:0002098	69.48	gold quality
bone marrow cell	CL:0002092	68.59	silver quality
ventricular zone	UBERON:0003053	68.51	gold quality
right adrenal gland	UBERON:0001233	67.51	gold quality
right adrenal gland cortex	UBERON:0035827	67.43	gold quality
ganglionic eminence	UBERON:0004023	66.34	gold quality
right testis	UBERON:0004534	65.41	gold quality
heart left ventricle	UBERON:0002084	64.34	gold quality
right frontal lobe	UBERON:0002810	64.25	gold quality
left adrenal gland	UBERON:0001234	64.18	gold quality
lower esophagus	UBERON:0013473	64.10	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.08	gold quality
left testis	UBERON:0004533	64.07	gold quality
left adrenal gland cortex	UBERON:0035825	63.68	gold quality
testis	UBERON:0000473	63.51	gold quality
adrenal gland	UBERON:0002369	63.48	gold quality
frontal cortex	UBERON:0001870	63.08	gold quality
lymph node	UBERON:0000029	63.05	gold quality
bone marrow	UBERON:0002371	62.88	gold quality
gall bladder	UBERON:0002110	62.75	gold quality
right lobe of liver	UBERON:0001114	62.67	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.54	gold quality
superior frontal gyrus	UBERON:0002661	62.37	gold quality
mucosa of transverse colon	UBERON:0004991	62.31	gold quality
granulocyte	CL:0000094	62.30	gold quality
mucosa of stomach	UBERON:0001199	61.98	gold quality
prefrontal cortex	UBERON:0000451	61.96	gold quality
cerebral cortex	UBERON:0000956	61.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.