PYCARD-AS1

Summary

PYCARD-AS1 (PYCARD antisense RNA 1, HGNC:45036) is a long non-coding RNA gene on chromosome 16p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45036
Approved symbol	PYCARD-AS1
Name	PYCARD antisense RNA 1
Location	16p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261359
Ensembl biotype	lncRNA
Entrez	100652740
RNAcentral	URS000075A9EB — lncRNA, 1109 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000561916, ENST00000812284, ENST00000812285

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561916 — 2 exons

Exon	Start	End
ENSE00004211146	31202460	31203452
ENSE00004211148	31201871	31201986

Expression profiles

Bgee: expression breadth ubiquitous, 147 present calls, max score 78.58.

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	78.58	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.96	silver quality
epithelium of nasopharynx	UBERON:0001951	75.16	gold quality
superficial temporal artery	UBERON:0001614	72.19	gold quality
mucosa of transverse colon	UBERON:0004991	72.11	gold quality
granulocyte	CL:0000094	71.74	gold quality
sperm	CL:0000019	70.91	gold quality
leukocyte	CL:0000738	70.37	gold quality
monocyte	CL:0000576	70.22	gold quality
gingival epithelium	UBERON:0001949	69.34	gold quality
mammary duct	UBERON:0001765	67.33	gold quality
cerebellar vermis	UBERON:0004720	66.60	gold quality
stromal cell of endometrium	CL:0002255	66.56	gold quality
saphenous vein	UBERON:0007318	66.31	gold quality
subthalamic nucleus	UBERON:0001906	66.17	gold quality
vena cava	UBERON:0004087	66.14	gold quality
tongue	UBERON:0001723	66.04	gold quality
trachea	UBERON:0003126	65.98	gold quality
body of tongue	UBERON:0011876	65.96	gold quality
superior surface of tongue	UBERON:0007371	65.82	gold quality
germinal epithelium of ovary	UBERON:0001304	65.81	gold quality
bone marrow cell	CL:0002092	65.75	silver quality
pharyngeal mucosa	UBERON:0000355	65.70	gold quality
dorsal plus ventral thalamus	UBERON:0001897	65.67	gold quality
corpus callosum	UBERON:0002336	65.55	gold quality
cardia of stomach	UBERON:0001162	65.38	gold quality
blood	UBERON:0000178	65.36	gold quality
ventral tegmental area	UBERON:0002691	65.35	gold quality
inferior vagus X ganglion	UBERON:0005363	65.22	gold quality
pericardium	UBERON:0002407	65.18	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	3163.57
E-ANND-3	yes	6.87

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.