PYDC2-AS1

Summary

PYDC2-AS1 (PYDC2 antisense RNA 1, HGNC:52874) is a long non-coding RNA gene on chromosome 3q28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52874
Approved symbol	PYDC2-AS1
Name	PYDC2 antisense RNA 1
Location	3q28
Locus type	RNA, long non-coding
Status	Approved
Aliases	LINCR-0002, RP11-197K6.1
Ensembl gene	ENSG00000223812
Ensembl biotype	lncRNA
Entrez	103344926
RNAcentral	URS000075BF72 — lncRNA, 1182 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 43 — 43 lncRNA

ENST00000438488, ENST00000439804, ENST00000641055, ENST00000641158, ENST00000642133, ENST00000651548, ENST00000653490, ENST00000655253, ENST00000656380, ENST00000656942, ENST00000657540, ENST00000658347, ENST00000660290, ENST00000661029, ENST00000661668, ENST00000662007, ENST00000662578, ENST00000662906, ENST00000663647, ENST00000664223, ENST00000664732, ENST00000664994, ENST00000666456, ENST00000666632, ENST00000667184, ENST00000668276, ENST00000668751, ENST00000669360, ENST00000669884, ENST00000671595, ENST00000744851, ENST00000744852, ENST00000744853, ENST00000744854, ENST00000744855, ENST00000744856, ENST00000744857, ENST00000744858, ENST00000744859, ENST00000744860, ENST00000744861, ENST00000744862, ENST00000744863

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438488 — 3 exons

Exon	Start	End
ENSE00001682862	191573314	191573509
ENSE00001709763	191569600	191569824
ENSE00001798642	191568535	191568607

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 86.23.

FANTOM5 (CAGE): breadth broad, TPM avg 2.3955 / max 141.2489, expressed in 275 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
40599	2.3955	275

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.23	gold quality
superior frontal gyrus	UBERON:0002661	83.13	gold quality
right frontal lobe	UBERON:0002810	82.38	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	81.68	gold quality
Brodmann (1909) area 9	UBERON:0013540	80.49	gold quality
frontal cortex	UBERON:0001870	77.87	gold quality
anterior cingulate cortex	UBERON:0009835	76.93	gold quality
primary visual cortex	UBERON:0002436	76.40	gold quality
cerebral cortex	UBERON:0000956	75.84	gold quality
prefrontal cortex	UBERON:0000451	74.23	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.99	gold quality
caudate nucleus	UBERON:0001873	69.72	gold quality
temporal lobe	UBERON:0001871	69.46	gold quality
amygdala	UBERON:0001876	69.45	gold quality
nucleus accumbens	UBERON:0001882	69.11	gold quality
cortical plate	UBERON:0005343	68.70	gold quality
brain	UBERON:0000955	67.56	gold quality
right adrenal gland cortex	UBERON:0035827	67.19	gold quality
sural nerve	UBERON:0015488	65.28	silver quality
putamen	UBERON:0001874	64.88	gold quality
left adrenal gland	UBERON:0001234	64.53	gold quality
right adrenal gland	UBERON:0001233	64.31	gold quality
adrenal gland	UBERON:0002369	63.82	gold quality
left adrenal gland cortex	UBERON:0035825	63.50	gold quality
right ovary	UBERON:0002118	63.00	gold quality
colonic epithelium	UBERON:0000397	61.83	silver quality
right atrium auricular region	UBERON:0006631	61.63	gold quality
ovary	UBERON:0000992	61.53	gold quality
left ovary	UBERON:0002119	61.08	gold quality
ventricular zone	UBERON:0003053	60.84	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-HCAD-35	yes	59.42
E-ANND-3	yes	5.56

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.