PYGO2-AS1

Summary

PYGO2-AS1 (PYGO2 and SHC1 antisense RNA 1, HGNC:55250) is a long non-coding RNA gene on chromosome 1q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55250
Approved symbol	PYGO2-AS1
Name	PYGO2 and SHC1 antisense RNA 1
Location	1q21.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL451085.2
Ensembl gene	ENSG00000271380
Ensembl biotype	lncRNA
Entrez	101928120
RNAcentral	URS000212314E — lncRNA, 1086 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000605085

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000605085 — 1 exons

Exon	Start	End
ENSE00003675032	154961825	154962623

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 89.75.

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.75	gold quality
pancreatic ductal cell	CL:0002079	86.00	silver quality
sural nerve	UBERON:0015488	82.89	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	80.53	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.51	gold quality
adenohypophysis	UBERON:0002196	73.08	gold quality
hindlimb stylopod muscle	UBERON:0004252	72.54	gold quality
pituitary gland	UBERON:0000007	71.37	gold quality
granulocyte	CL:0000094	70.54	gold quality
right adrenal gland	UBERON:0001233	70.22	gold quality
stromal cell of endometrium	CL:0002255	70.10	gold quality
tendon of biceps brachii	UBERON:0008188	70.07	silver quality
left adrenal gland cortex	UBERON:0035825	69.81	gold quality
right adrenal gland cortex	UBERON:0035827	69.77	gold quality
mucosa of transverse colon	UBERON:0004991	69.74	gold quality
left adrenal gland	UBERON:0001234	69.43	gold quality
gastrocnemius	UBERON:0001388	69.43	gold quality
ventricular zone	UBERON:0003053	69.20	gold quality
mucosa of stomach	UBERON:0001199	68.87	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	68.85	gold quality
muscle of leg	UBERON:0001383	68.63	gold quality
lower esophagus	UBERON:0013473	68.56	gold quality
lower esophagus muscularis layer	UBERON:0035833	68.56	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	68.51	gold quality
muscle layer of sigmoid colon	UBERON:0035805	68.18	gold quality
adrenal cortex	UBERON:0001235	67.75	gold quality
left lobe of thyroid gland	UBERON:0001120	67.63	gold quality
metanephros cortex	UBERON:0010533	67.42	gold quality
cortical plate	UBERON:0005343	67.28	gold quality
adrenal gland	UBERON:0002369	66.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.