RAB27B-AS1

Summary

RAB27B-AS1 (RAB27B antisense RNA 1, HGNC:58316) is a long non-coding RNA gene on chromosome 18q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58316
Approved symbol	RAB27B-AS1
Name	RAB27B antisense RNA 1
Location	18q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267112
Ensembl biotype	lncRNA
Entrez	139440219
RNAcentral	URS0002A3823B — lncRNA, 631 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000588466, ENST00000795400

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000588466 — 4 exons

Exon	Start	End
ENSE00002736113	54897926	54898083
ENSE00002880498	54885866	54885892
ENSE00002888996	54891145	54891430
ENSE00002935586	54888064	54888159

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 90.31.

Top tissues by expression

109 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	90.31	gold quality
cortical plate	UBERON:0005343	66.30	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.66	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.06	gold quality
prefrontal cortex	UBERON:0000451	59.40	gold quality
monocyte	CL:0000576	58.00	gold quality
lower esophagus mucosa	UBERON:0035834	56.25	gold quality
duodenum	UBERON:0002114	56.08	gold quality
islet of Langerhans	UBERON:0000006	55.69	gold quality
adrenal tissue	UBERON:0018303	54.39	gold quality
calcaneal tendon	UBERON:0003701	53.92	gold quality
body of stomach	UBERON:0001161	53.73	gold quality
stomach	UBERON:0000945	53.53	gold quality
esophagus mucosa	UBERON:0002469	53.50	gold quality
blood	UBERON:0000178	53.48	gold quality
placenta	UBERON:0001987	53.41	gold quality
liver	UBERON:0002107	53.17	gold quality
left testis	UBERON:0004533	52.63	gold quality
gall bladder	UBERON:0002110	52.12	gold quality
testis	UBERON:0000473	51.82	gold quality
ectocervix	UBERON:0012249	51.75	gold quality
esophagus	UBERON:0001043	51.12	gold quality
right lobe of liver	UBERON:0001114	50.91	silver quality
primary visual cortex	UBERON:0002436	50.87	gold quality
pancreas	UBERON:0001264	50.24	gold quality
endometrium	UBERON:0001295	49.62	gold quality
urinary bladder	UBERON:0001255	49.47	gold quality
body of pancreas	UBERON:0001150	49.40	gold quality
rectum	UBERON:0001052	49.39	gold quality
muscle of leg	UBERON:0001383	49.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.88

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.