RASGRF2-AS1

Summary

RASGRF2-AS1 (RASGRF2 antisense RNA 1, HGNC:40499) is a long non-coding RNA gene on chromosome 5q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40499
Approved symbol	RASGRF2-AS1
Name	RASGRF2 antisense RNA 1
Location	5q14.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTC-459I6.1
Ensembl gene	ENSG00000251450
Ensembl biotype	lncRNA
Entrez	102524628
RNAcentral	URS000075D616 — lncRNA, 539 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000505107, ENST00000505694, ENST00000660640, ENST00000667579, ENST00000772315, ENST00000772316, ENST00000772317, ENST00000772318, ENST00000772319, ENST00000772320, ENST00000772321, ENST00000772322, ENST00000772323, ENST00000772324

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505107 — 2 exons

Exon	Start	End
ENSE00002042056	80952668	80952980
ENSE00002045357	80951129	80951480

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 80.48.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0858 / max 7.7052, expressed in 39 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
62316	0.0858	39

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	80.48	gold quality
superior frontal gyrus	UBERON:0002661	77.01	gold quality
anterior cingulate cortex	UBERON:0009835	75.46	gold quality
right frontal lobe	UBERON:0002810	75.32	gold quality
frontal cortex	UBERON:0001870	75.10	gold quality
prefrontal cortex	UBERON:0000451	74.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.78	gold quality
cerebral cortex	UBERON:0000956	74.28	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	74.00	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.91	gold quality
primary visual cortex	UBERON:0002436	73.88	gold quality
amygdala	UBERON:0001876	72.50	gold quality
temporal lobe	UBERON:0001871	72.41	gold quality
Ammon’s horn	UBERON:0001954	72.09	gold quality
substantia nigra	UBERON:0002038	71.24	gold quality
corpus callosum	UBERON:0002336	71.12	gold quality
putamen	UBERON:0001874	68.34	gold quality
brain	UBERON:0000955	68.10	gold quality
left ovary	UBERON:0002119	67.73	gold quality
caudate nucleus	UBERON:0001873	67.26	gold quality
hypothalamus	UBERON:0001898	67.22	gold quality
ovary	UBERON:0000992	66.78	gold quality
cortical plate	UBERON:0005343	65.56	gold quality
tibial nerve	UBERON:0001323	64.91	gold quality
right ovary	UBERON:0002118	64.77	gold quality
omental fat pad	UBERON:0010414	64.77	gold quality
colonic epithelium	UBERON:0000397	63.73	silver quality
adipose tissue	UBERON:0001013	63.66	gold quality
skeletal muscle tissue	UBERON:0001134	63.38	gold quality
subcutaneous adipose tissue	UBERON:0002190	62.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.