RBFADN

Summary

RBFADN (RBFA downstream neighbor, HGNC:48591) is a long non-coding RNA gene on chromosome 18q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48591
Approved symbol	RBFADN
Name	RBFA downstream neighbor
Location	18q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261126
Ensembl biotype	lncRNA
Entrez	100506070
RNAcentral	URS000075D449 — lncRNA, 808 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000562391, ENST00000564686, ENST00000566810, ENST00000568911

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000562391 — 5 exons

Exon	Start	End
ENSE00002576217	80046900	80047425
ENSE00002591388	80080781	80081293
ENSE00003704116	80079687	80079808
ENSE00003708454	80069798	80069906
ENSE00003709462	80048114	80048193

Expression profiles

Bgee: expression breadth ubiquitous, 154 present calls, max score 75.80.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0118 / max 12.6237, expressed in 5 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
170922	0.0073	3
208615	0.0044	3

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	75.80	gold quality
right hemisphere of cerebellum	UBERON:0014890	73.58	gold quality
cerebellar hemisphere	UBERON:0002245	73.50	gold quality
cerebellar cortex	UBERON:0002129	73.41	gold quality
bone marrow cell	CL:0002092	72.86	gold quality
cerebellum	UBERON:0002037	71.12	gold quality
ventricular zone	UBERON:0003053	70.47	gold quality
right ovary	UBERON:0002118	69.34	gold quality
left ovary	UBERON:0002119	69.19	gold quality
cortical plate	UBERON:0005343	69.19	gold quality
right frontal lobe	UBERON:0002810	68.72	gold quality
ganglionic eminence	UBERON:0004023	68.40	gold quality
muscle layer of sigmoid colon	UBERON:0035805	68.18	gold quality
Brodmann (1909) area 9	UBERON:0013540	68.17	gold quality
endocervix	UBERON:0000458	68.00	gold quality
colonic epithelium	UBERON:0000397	67.99	silver quality
hindlimb stylopod muscle	UBERON:0004252	67.94	gold quality
stromal cell of endometrium	CL:0002255	67.46	gold quality
anterior cingulate cortex	UBERON:0009835	67.45	gold quality
body of uterus	UBERON:0009853	66.95	gold quality
tibial artery	UBERON:0007610	66.83	gold quality
popliteal artery	UBERON:0002250	66.82	gold quality
tibial nerve	UBERON:0001323	66.72	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.42	gold quality
hypothalamus	UBERON:0001898	66.23	gold quality
nucleus accumbens	UBERON:0001882	66.11	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.08	gold quality
muscle of leg	UBERON:0001383	66.04	gold quality
mucosa of stomach	UBERON:0001199	66.01	gold quality
gastrocnemius	UBERON:0001388	66.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.