RBM15-AS1

Summary

RBM15-AS1 (RBM15 antisense RNA 1, HGNC:53636) is a long non-coding RNA gene on chromosome 1p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53636
Approved symbol	RBM15-AS1
Name	RBM15 antisense RNA 1
Location	1p13.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AS-RBM15
Ensembl gene	ENSG00000227963
Ensembl biotype	lncRNA
Entrez	440600
RNAcentral	URS000075C697 — lncRNA, 2671 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 30 — 30 lncRNA

ENST00000449169, ENST00000686992, ENST00000748880, ENST00000748881, ENST00000748882, ENST00000748883, ENST00000748884, ENST00000748885, ENST00000748886, ENST00000748887, ENST00000748888, ENST00000748889, ENST00000748890, ENST00000748891, ENST00000748892, ENST00000748893, ENST00000748894, ENST00000748895, ENST00000748896, ENST00000748897, ENST00000748898, ENST00000748899, ENST00000748900, ENST00000748901, ENST00000748902, ENST00000748903, ENST00000748904, ENST00000748905, ENST00000748906, ENST00000748907

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449169 — 4 exons

Exon	Start	End
ENSE00001609568	110286375	110288571
ENSE00001637184	110318765	110318882
ENSE00001722420	110292387	110292507
ENSE00001796033	110338997	110339171

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 72.50.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8339 / max 20.0259, expressed in 470 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
13739	0.8339	470

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	72.50	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.22	silver quality
hindlimb stylopod muscle	UBERON:0004252	59.85	gold quality
ventricular zone	UBERON:0003053	59.48	silver quality
cortical plate	UBERON:0005343	56.26	silver quality
skeletal muscle tissue	UBERON:0001134	56.07	gold quality
blood	UBERON:0000178	55.19	gold quality
leukocyte	CL:0000738	55.08	silver quality
monocyte	CL:0000576	54.69	silver quality
granulocyte	CL:0000094	54.55	gold quality
right hemisphere of cerebellum	UBERON:0014890	54.37	gold quality
cerebellar hemisphere	UBERON:0002245	54.17	gold quality
cerebellum	UBERON:0002037	54.12	gold quality
cerebellar cortex	UBERON:0002129	54.12	gold quality
muscle of leg	UBERON:0001383	53.08	gold quality
lymph node	UBERON:0000029	52.80	gold quality
islet of Langerhans	UBERON:0000006	52.64	gold quality
tonsil	UBERON:0002372	52.40	gold quality
stromal cell of endometrium	CL:0002255	52.37	silver quality
gastrocnemius	UBERON:0001388	52.28	gold quality
liver	UBERON:0002107	50.35	silver quality
duodenum	UBERON:0002114	50.11	gold quality
bone marrow	UBERON:0002371	49.95	silver quality
small intestine	UBERON:0002108	49.71	gold quality
prefrontal cortex	UBERON:0000451	49.49	silver quality
small intestine Peyer’s patch	UBERON:0003454	49.46	gold quality
urinary bladder	UBERON:0001255	49.38	gold quality
right lobe of liver	UBERON:0001114	49.30	silver quality
mucosa of transverse colon	UBERON:0004991	49.28	gold quality
spleen	UBERON:0002106	48.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.04

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.