RC3H1-DT

Summary

RC3H1-DT (RC3H1 divergent transcript, HGNC:54295) is a long non-coding RNA gene on chromosome 1q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54295
Approved symbol	RC3H1-DT
Name	RC3H1 divergent transcript
Location	1q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224977
Ensembl biotype	lncRNA
Entrez	105371620
RNAcentral	URS00026A216A — lncRNA, 566 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000424181, ENST00000688280, ENST00000726555

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424181 — 2 exons

Exon	Start	End
ENSE00004051201	174022435	174022640
ENSE00004051203	174022783	174023191

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 85.21.

FANTOM5 (CAGE): breadth broad, TPM avg 3.3822 / max 225.8831, expressed in 791 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
6752	1.1967	367
6753	1.1227	326
6751	1.0628	442

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	85.21	gold quality
testis	UBERON:0000473	84.40	gold quality
right testis	UBERON:0004534	83.74	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.34	gold quality
bone marrow cell	CL:0002092	73.68	gold quality
granulocyte	CL:0000094	71.53	gold quality
lymph node	UBERON:0000029	69.86	gold quality
bone marrow	UBERON:0002371	67.77	gold quality
leukocyte	CL:0000738	64.28	gold quality
monocyte	CL:0000576	63.88	gold quality
gall bladder	UBERON:0002110	61.22	gold quality
islet of Langerhans	UBERON:0000006	60.70	gold quality
prefrontal cortex	UBERON:0000451	60.21	gold quality
muscle of leg	UBERON:0001383	59.87	gold quality
gastrocnemius	UBERON:0001388	59.77	gold quality
blood	UBERON:0000178	59.16	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.06	gold quality
superior frontal gyrus	UBERON:0002661	58.96	gold quality
calcaneal tendon	UBERON:0003701	58.88	gold quality
placenta	UBERON:0001987	58.22	gold quality
vermiform appendix	UBERON:0001154	57.52	gold quality
smooth muscle tissue	UBERON:0001135	57.38	gold quality
liver	UBERON:0002107	57.13	gold quality
right uterine tube	UBERON:0001302	56.97	gold quality
right lobe of liver	UBERON:0001114	56.52	gold quality
fallopian tube	UBERON:0003889	56.33	gold quality
adult mammalian kidney	UBERON:0000082	54.78	gold quality
tonsil	UBERON:0002372	54.20	gold quality
kidney	UBERON:0002113	54.04	gold quality
urinary bladder	UBERON:0001255	53.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.68

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.