RCC2-AS1

Summary

RCC2-AS1 (RCC2 antisense RNA 1, HGNC:41262) is a long non-coding RNA gene on chromosome 1p36.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41262
Approved symbol	RCC2-AS1
Name	RCC2 antisense RNA 1
Location	1p36.13
Locus type	RNA, long non-coding
Status	Approved
Aliases	LCPAT1, ENST00000439577
Ensembl gene	ENSG00000227751
Ensembl biotype	lncRNA
Entrez	114515514
RNAcentral	URS000212324F — lncRNA, 310 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000439577

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439577 — 2 exons

Exon	Start	End
ENSE00001592820	17406760	17407004
ENSE00001710950	17407317	17407382

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 96.52.

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tonsil	UBERON:0002372	96.52	gold quality
bone marrow cell	CL:0002092	94.82	gold quality
placenta	UBERON:0001987	93.92	gold quality
lower esophagus mucosa	UBERON:0035834	90.50	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.38	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.94	gold quality
colonic epithelium	UBERON:0000397	88.91	gold quality
monocyte	CL:0000576	88.16	gold quality
primary visual cortex	UBERON:0002436	87.61	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	84.66	gold quality
ventricular zone	UBERON:0003053	84.60	gold quality
sural nerve	UBERON:0015488	84.30	gold quality
ganglionic eminence	UBERON:0004023	83.34	gold quality
leukocyte	CL:0000738	83.23	gold quality
adrenal tissue	UBERON:0018303	81.76	gold quality
urinary bladder	UBERON:0001255	81.75	gold quality
thoracic mammary gland	UBERON:0005200	81.11	gold quality
muscle tissue	UBERON:0002385	79.90	gold quality
mucosa of transverse colon	UBERON:0004991	78.96	gold quality
superior frontal gyrus	UBERON:0002661	78.21	gold quality
kidney	UBERON:0002113	78.04	gold quality
skeletal muscle tissue	UBERON:0001134	77.81	gold quality
uterine cervix	UBERON:0000002	77.67	gold quality
liver	UBERON:0002107	77.32	gold quality
myometrium	UBERON:0001296	76.50	gold quality
prefrontal cortex	UBERON:0000451	75.84	gold quality
Ammon’s horn	UBERON:0001954	75.80	gold quality
cortex of kidney	UBERON:0001225	75.65	gold quality
hypothalamus	UBERON:0001898	75.52	gold quality
adult mammalian kidney	UBERON:0000082	75.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LCPAT1, through RCC2, is involved in the cigarette smoke exposure-induced DNA damage providing new insight into the lung carcinogenesis related to cigarette smoking. (PMID:30509493)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.