RELA-DT

Summary

RELA-DT (RELA divergent transcript, HGNC:54185) is a long non-coding RNA gene on chromosome 11q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54185
Approved symbol	RELA-DT
Name	RELA divergent transcript
Location	11q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000285533
Ensembl biotype	lncRNA
Entrez	105369347
RNAcentral	URS00026A2748 — lncRNA, 624 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 54 — 54 lncRNA

ENST00000648185, ENST00000654031, ENST00000654110, ENST00000685480, ENST00000689251, ENST00000690559, ENST00000690937, ENST00000691526, ENST00000692111, ENST00000820174, ENST00000820175, ENST00000820176, ENST00000820177, ENST00000820178, ENST00000820179, ENST00000820180, ENST00000820181, ENST00000820182, ENST00000820183, ENST00000820184, ENST00000820185, ENST00000820186, ENST00000820187, ENST00000820188, ENST00000820189, ENST00000820190, ENST00000820191, ENST00000820192, ENST00000820193, ENST00000820194, ENST00000820195, ENST00000820196, ENST00000820197, ENST00000820198, ENST00000820199, ENST00000820200, ENST00000820201, ENST00000820202, ENST00000820203, ENST00000820204, ENST00000820205, ENST00000820206, ENST00000820207, ENST00000820208, ENST00000820209, ENST00000820210, ENST00000820211, ENST00000820212, ENST00000820213, ENST00000820214, ENST00000820215, ENST00000820216, ENST00000820217, ENST00000820218

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000648185 — 5 exons

Exon	Start	End
ENSE00003838032	65663427	65663683
ENSE00003838076	65665421	65665543
ENSE00003839436	65666131	65666217
ENSE00003987565	65671423	65671718
ENSE00004225937	65662981	65663148

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 83.09.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.9204 / max 239.8270, expressed in 1682 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
115198	2.2941	1212
115202	1.7625	696
115199	1.1311	589
115200	0.6080	170
115201	0.1248	37

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	83.09	gold quality
gastrocnemius	UBERON:0001388	82.12	gold quality
muscle of leg	UBERON:0001383	81.60	gold quality
apex of heart	UBERON:0002098	80.86	gold quality
left testis	UBERON:0004533	80.79	gold quality
testis	UBERON:0000473	80.27	gold quality
right testis	UBERON:0004534	80.02	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.73	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	79.59	gold quality
skeletal muscle tissue	UBERON:0001134	78.77	gold quality
granulocyte	CL:0000094	78.25	gold quality
substantia nigra	UBERON:0002038	76.65	gold quality
muscle tissue	UBERON:0002385	75.58	gold quality
blood	UBERON:0000178	75.41	gold quality
putamen	UBERON:0001874	74.05	gold quality
leukocyte	CL:0000738	74.01	gold quality
monocyte	CL:0000576	73.69	gold quality
Ammon’s horn	UBERON:0001954	73.49	gold quality
heart left ventricle	UBERON:0002084	73.41	gold quality
right adrenal gland cortex	UBERON:0035827	73.31	gold quality
right lobe of liver	UBERON:0001114	73.26	gold quality
muscle layer of sigmoid colon	UBERON:0035805	72.96	gold quality
right adrenal gland	UBERON:0001233	72.95	gold quality
lower esophagus muscularis layer	UBERON:0035833	72.91	gold quality
lower esophagus	UBERON:0013473	72.86	gold quality
left adrenal gland cortex	UBERON:0035825	72.77	gold quality
spleen	UBERON:0002106	72.74	gold quality
amygdala	UBERON:0001876	72.72	gold quality
temporal lobe	UBERON:0001871	72.67	gold quality
left adrenal gland	UBERON:0001234	72.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.02

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.