RENO1

Summary

RENO1 (regulator of early neurogenesis 1, HGNC:54096) is a long non-coding RNA gene on chromosome 17q25.3.

Predicted to act upstream of or within chromatin organization; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus.

Source: NCBI Gene 119545628 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54096
Approved symbol	RENO1
Name	regulator of early neurogenesis 1
Location	17q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000287431
Ensembl biotype	lncRNA
Entrez	119545628
RNAcentral	URS00026A22F1 — lncRNA, 6813 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000665286, ENST00000824862, ENST00000824863, ENST00000824864

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000665286 — 1 exons

Exon	Start	End
ENSE00004234554	81339183	81345986

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 66.29.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ganglionic eminence	UBERON:0004023	66.29	gold quality
cortical plate	UBERON:0005343	65.42	gold quality
colonic epithelium	UBERON:0000397	64.28	silver quality
stromal cell of endometrium	CL:0002255	63.01	gold quality
ventricular zone	UBERON:0003053	61.10	gold quality
lower esophagus mucosa	UBERON:0035834	58.28	gold quality
mucosa of transverse colon	UBERON:0004991	57.32	gold quality
cerebellum	UBERON:0002037	56.22	gold quality
cerebellar hemisphere	UBERON:0002245	56.19	gold quality
cerebellar cortex	UBERON:0002129	56.17	gold quality
right hemisphere of cerebellum	UBERON:0014890	56.15	gold quality
lower esophagus muscularis layer	UBERON:0035833	56.12	gold quality
lower esophagus	UBERON:0013473	56.09	gold quality
gastrocnemius	UBERON:0001388	55.89	gold quality
sural nerve	UBERON:0015488	55.84	silver quality
skeletal muscle tissue	UBERON:0001134	55.74	gold quality
muscle of leg	UBERON:0001383	55.73	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.41	silver quality
myometrium	UBERON:0001296	55.10	gold quality
fundus of stomach	UBERON:0001160	54.98	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	54.97	gold quality
muscle layer of sigmoid colon	UBERON:0035805	53.86	gold quality
urinary bladder	UBERON:0001255	53.54	gold quality
body of uterus	UBERON:0009853	53.47	gold quality
left ovary	UBERON:0002119	53.43	gold quality
liver	UBERON:0002107	53.42	gold quality
esophagus	UBERON:0001043	53.35	gold quality
cortex of kidney	UBERON:0001225	53.27	gold quality
right lobe of thyroid gland	UBERON:0001119	53.12	gold quality
right lobe of liver	UBERON:0001114	53.05	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.