RETREG1-AS1

Summary

RETREG1-AS1 (RETREG1 antisense RNA 1, HGNC:55551) is a long non-coding RNA gene on chromosome 5p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55551
Approved symbol	RETREG1-AS1
Name	RETREG1 antisense RNA 1
Location	5p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246214
Ensembl biotype	lncRNA
Entrez	101929524
RNAcentral	URS000018CD8D — lncRNA, 1674 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000499131, ENST00000504935, ENST00000653650, ENST00000700847, ENST00000716636, ENST00000716637, ENST00000818082, ENST00000818083

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499131 — 4 exons

Exon	Start	End
ENSE00001959572	16615926	16616486
ENSE00001962208	16629454	16629969
ENSE00001963112	16625415	16625756
ENSE00001987453	16621778	16622032

Expression profiles

Bgee: expression breadth ubiquitous, 149 present calls, max score 84.53.

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.53	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.86	gold quality
colonic epithelium	UBERON:0000397	67.13	silver quality
right atrium auricular region	UBERON:0006631	67.12	gold quality
cardiac atrium	UBERON:0002081	66.44	gold quality
frontal pole	UBERON:0002795	66.17	gold quality
middle frontal gyrus	UBERON:0002702	65.93	gold quality
paraflocculus	UBERON:0005351	65.84	gold quality
left testis	UBERON:0004533	65.35	gold quality
right testis	UBERON:0004534	64.80	gold quality
testis	UBERON:0000473	63.27	gold quality
ventricular zone	UBERON:0003053	62.39	gold quality
cortical plate	UBERON:0005343	61.60	gold quality
sural nerve	UBERON:0015488	61.14	silver quality
ganglionic eminence	UBERON:0004023	60.55	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.55	gold quality
endometrium epithelium	UBERON:0004811	56.86	gold quality
islet of Langerhans	UBERON:0000006	56.66	gold quality
heart	UBERON:0000948	56.08	gold quality
metanephric glomerulus	UBERON:0004736	55.97	gold quality
prefrontal cortex	UBERON:0000451	55.38	gold quality
corpus callosum	UBERON:0002336	54.97	gold quality
cerebellar cortex	UBERON:0002129	54.78	gold quality
cerebellar hemisphere	UBERON:0002245	54.74	gold quality
right hemisphere of cerebellum	UBERON:0014890	54.53	gold quality
skin of abdomen	UBERON:0001416	54.27	gold quality
skin of leg	UBERON:0001511	54.26	gold quality
leukocyte	CL:0000738	54.16	gold quality
cerebellum	UBERON:0002037	54.03	gold quality
monocyte	CL:0000576	53.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.